Streptococcus pneumoniae inflicts a huge disease burden as the leading cause of
community-acquired pneumonia and meningitis. Soon after mainstream antibiotic usage …

To overview the present global burden of pneumococcal disease is important because new
preventive measures such as the pneumococcal conjugate vaccine 13 are currently being …

Background Reducing the burden of death due to infection is an urgent global public health
priority. Previous studies have estimated the number of deaths associated with drug …

Evidence-based guidelines for the diagnosis and initial management of suspected acute
bacterial rhinosinusitis in adults and children were prepared by a multidisciplinary expert …

Importance Vaccine responses are decreased in solid organ transplant (SOT) recipients,
and given the complexity of implementation, vaccination programs may be suboptimal. The …

Pneumococcal polysaccharide vaccines (PPVs) and conjugate vaccines (PCVs), of which
PPV23 and PCV13 are the current front runners, have had a significant, beneficial impact on …

Following usage of the pneumococcal conjugate vaccine in children, the incidence of
invasive pneumococcal disease declined in both children and adults (reflecting herd …

Sepsis-associated encephalopathy manifesting as delirium is a common problem in critical
care medicine. In this study, patients that had delirium due to sepsis had significant cognitive …

Background Unlike free pneumococcal polysaccharide vaccines (PPSVs), pneumococcal
conjugate vaccines (PCVs) induce a T–cell–dependent immune response. The study …

Background: Pneumococcal conjugate vaccines (PCV) are emerging as one of the most
promising means to prevent pediatric disease. The 7-valent PCV (PCV-7) has been …