Objective: The aim of this study was to determine the frequency of germline variants in
BRCA1, BRCA2, CDH1, PALB2, PTEN and TP53 in patients admitted to a medical genetics …

Breast cancer is the most common malignancy diagnosed in women (after skin cancer) in
the United States. 1 In 2020, an estimated 276,480 women were diagnosed with breast …

Objective: To evaluate the outcomes of breast cancer (BC) patients in Naradhiwas
Rajanagarindra Hospital and factors associated with the outcomes. Material and Methods: A …

Simple Summary The NCCN Clinical Practice Guidelines are testing criteria used to identify
high-risk individuals associated with an increased risk of breast, ovarian, pancreatic, and …

There is limited information known about how women with pathogenic variants (PV) in
moderate penetrance genes make decisions to manage their increased risk of breast …

Introduction The objective of this study was to determine the incidence of textbook oncologic
outcome (TOO) and its impact on overall survival (OS) among patients with invasive ductal …

About 5-10% of malignant neoplasms (MN) are hereditary. Carriers of mutations associated
with hereditary tumor syndromes (HTS) are at high risk of developing tumors in childhood …

Purpose BRCA1/2 pathogenic variant (PV) mutations confer radiation sensitivity
preclinically, but there are limited data regarding breast cancer outcomes after radiation …

Breast cancer is the most common cancer among women. In Bosnia and Herzegovina (BiH),
accurate data on the status of breast cancer are lacking due to the absence of a central …

When BRCA1 and BRCA2 were first identified, the initial models for delivering testing were
shaped by concepts of genetic exceptionalism and a lack of data regarding therapeutic …