Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …

Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic
homeostasis of this essential trace element. This review summarizes the key aspects of …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc (Zn) nutritional importance has been known for a long time, but in the last decades its
importance in immune modulation has arisen. This review aims at describing the …

Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …

Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for
enzymes that are involved in critical biochemical processes and it plays many structural …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

Iron and zinc are essential micronutrients required for growth and health. Deficiencies of
these nutrients are highly prevalent among populations, but can be alleviated by …

Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …

ZIP8 (SLC39A8) belongs to the ZIP family of metal-ion transporters. Among the ZIP proteins,
ZIP8 is most closely related to ZIP14, which can transport iron, zinc, manganese, and …