Our understanding of the genetics of congenital heart disease (CHD) is rapidly expanding;
however, many questions, particularly those relating to sporadic forms of disease, remain …

Fetal imaging is a burgeoning topic. New advancements in both magnetic resonance
imaging and (3D) ultrasound currently allow doctors to diagnose fetal structural …

Congenital heart disease (CHD) is a multifaceted cardiovascular anomaly that occurs when
there are structural abnormalities in the heart before birth. Although various risk factors are …

Congenital heart disease is the most common congenital anomaly, representing an
important cause of infant morbidity and mortality. Congenital heart disease represents a …

Cardiovascular diseases (CVDs) are considered as the leading cause of death worldwide.
CVD continues to be a major cause of death and morbidity despite significant improvements …

Cardiac development relies on proper cardiomyocyte differentiation, including expression
and assembly of cell-type-specific actomyosin subunits into a functional cardiac sarcomere …

Nav1. 5 is the predominant cardiac sodium channel subtype, encoded by the SCN5A gene,
which is involved in the initiation and conduction of action potentials throughout the heart …

Abstract The Human Genome Project (HGP), as the primary sequencing of the human
genome, lasted more than one decade to be completed using the traditional Sanger's …

Congenital heart disease (CHD) is the most common type of developmental abnormality in
humans, and is a leading cause for substantially increased morbidity and mortality in …

Bicuspid aortic valve (BAV) is the most common congenital heart defect (CHD), affecting 1–
2% of the population. BAV is associated with thoracic aortic aneurysms (TAAs). Deleterious …