[HTML][HTML] Review finds core outcome set uptake in new studies and systematic reviews needs improvement

PR Williamson, H Barrington, JM Blazeby… - Journal of Clinical …, 2022 - Elsevier
Objectives To review evidence about the uptake of core outcome sets (COS). A COS is an
agreed standardized set of outcomes that should be measured and reported, as a minimum …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 13 January 2023

World Health Organization - 2023 - apps.who.int
As of December 2022, there have been over 642 million confirmed cases of COVID-19 (10).
The pandemic has thus far claimed approximately 6.62 million lives (10). Vaccination is …

[HTML][HTML] A framework for prospective, adaptive meta-analysis (FAME) of aggregate data from randomised trials

JF Tierney, DJ Fisher, CL Vale, S Burdett… - PLoS …, 2021 - journals.plos.org
Background The vast majority of systematic reviews are planned retrospectively, once most
eligible trials have completed and reported, and are based on aggregate data that can be …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 31 March 2021

World Health Organization - 2021 - apps.who.int
what is this living guideline? Clinical question: What is the role of drugs in the treatment of
patients with COVID-19? Target audience: The target audiences are clinicians and health …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 14 July 2022

World Health Organization - 2022 - apps.who.int
As of May 2022, there have been over 524 million confirmed cases of COVID-19 (10). The
pandemic has thus far claimed approximately 6.2 million lives (10). Vaccination is having a …

Combination therapies for COVID‐19: An overview of the clinical trials landscape

S Akinbolade, D Coughlan, R Fairbairn… - British journal of …, 2022 - Wiley Online Library
The COVID‐19 pandemic has driven an unprecedented level of global activity in drug
discovery and clinical development for effective therapeutics targeting the coronavirus …

Evaluation of data sharing after implementation of the International Committee of Medical Journal Editors data sharing statement requirement

V Danchev, Y Min, J Borghi, M Baiocchi… - JAMA network …, 2021 - jamanetwork.com
Importance The benefits of responsible sharing of individual-participant data (IPD) from
clinical studies are well recognized, but stakeholders often disagree on how to align those …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 20 November 2020

World Health Organization - 2020 - apps.who.int
WHAT IS THIS LIVING GUIDELINE? Clinical question: What is the role of drugs in the
treatment of patients with COVID-19? Target audience: The target audience is clinicians and …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 22 April 2022

World Health Organization - 2022 - apps.who.int
As of 15 April 2022, there have been over 502 million confirmed cases of COVID-19 (10).
The pandemic has thus far claimed approximately 6.2 million lives (10). Vaccination is …

Funding Sources of Therapeutic and Vaccine Clinical Trials for COVID-19 vs Non–COVID-19 Indications, 2020-2021

A Angelis, CS Alonso, I Kyriopoulos… - JAMA network …, 2022 - jamanetwork.com
Importance Effective COVID-19 vaccines and therapeutics reached the market within the first
year of the pandemic. This rate of development and availability was an unprecedented …