Perivascular spaces (PVS) and blood–brain barrier (BBB) disruption are two key features of
cerebral small vessel disease (cSVD) and neurodegenerative diseases that have been …

The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a
complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound …

Astrocytes (ACs) are the most abundant cells in the brain and, importantly, are the master
connecting and communicating cells that provide structural and functional support for brain …

Blast-related mild traumatic brain injury (mTBI) is recognized as the “signature injury” of the
Iraq and Afghanistan wars. Sleep disruption, mTBI, and neuroinflammation have been …

Background: Growing evidence links brain-MRI enlarged perivascular spaces (EPVS) and
multiple sclerosis (MS), but their role remains unclear. Objective: This study aimed to …

The intricate relationship between the central nervous system (CNS) and the immune
system plays a crucial role in the pathogenesis of various neurological diseases …

Brain spaces around (perivascular spaces) and alongside (paravascular or Virchow–Robin
spaces) vessels have gained significant attention in recent years due to the advancements …

Pericyte (s)(Pcs) and resident perivascular macrophages (rPVMΦs) are positioned perfectly
in the neurovascular unit (NVU) and perivascular spaces to facilitate metainflammation that …

Background and Purpose Perivascular spaces (PVS) are interstitial fluid-filled spaces
surrounding blood vessels traversing the deep gray nuclei and white matter of the brain …

Background: Perivascular space (PVS) enlargement in ageing and Alzheimer's disease
(AD) and its exacerbators require further investigation. Methods: We studied centrum …