The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Novel diagnostic stewardship in infectious disease consists of interventions that modify
ordering, processing, and reporting of diagnostic tests to provide the right test for the right …

Immunocompromised patients account for an increasing proportion of the typical intensive
care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and …

Antibiotic resistance is a major health problem and will be probably one of the leading
causes of deaths in the coming years. One of the most effective ways to fight against …

Antimicrobial resistance (AMR) among bacteria is an escalating public health emergency
that has worsened during the COVID-19 pandemic. When making antibiotic treatment …

Real-time polymerase chain reaction (qPCR) enables accurate detection and quantification
of nucleic acids and has become a fundamental tool in biological sciences, bioengineering …

Objectives We aimed at assessing the efficacy and safety on antibiotic exposure of a
strategy combining a respiratory multiplex PCR (mPCR) with enlarged panel and daily …

Background No univocal recommendation exists for microbiological diagnosis of ventilator-
associated pneumonia (VAP). Sampling of either proximal or distal respiratory tract likely …

Immunocompromised patients—including patients with cancer, hematological malignancies,
solid organ transplants and individuals receiving immunosuppressive therapies for …

RMD hold great value in simplifying patient management and mitigating antimicrobial
exposure, particularly in settings with high levels of antimicrobial resistance where the use of …