Expanding the arsenal against pulmonary diseases using surface-functionalized polymeric micelles: Breakthroughs and bottlenecks

R Khursheed, KR Paudel, M Gulati, S Vishwas… - …, 2022 - Taylor & Francis
Pulmonary diseases such as lung cancer, asthma and tuberculosis have remained one of
the common challenges globally. Polymeric micelles (PMs) have emerged as an effective …

A narrative review on trans-nasal pulmonary aerosol delivery

J Li, JB Fink, R MacLoughlin, R Dhand - Critical Care, 2020 - Springer
The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has
expanded in recent years. However, various factors influencing aerosol delivery in this …

Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport

V Lenders, X Koutsoumpou, P Phan… - Chemical Society …, 2023 - pubs.rsc.org
The biomedical use of nanoparticles (NPs) has been the focus of intense research for over a
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …

High flow nasal cannula use is associated with increased hospital length of stay for pediatric asthma

C Rogerson, A Owora, T He, A Carroll… - Pediatric …, 2023 - Wiley Online Library
Background High flow nasal cannula (HFNC) is a respiratory device increasingly used to
treat asthma. Recent mechanistic studies have shown that nebulized medications may have …

Individualized aerosol medicine: Integrating device into the patient

A Ari, N Raghavan, M Diaz, BK Rubin… - Paediatric Respiratory …, 2023 - Elsevier
Pulmonary drug delivery is complex due to several challenges including disease-, patient-,
and clinicians-related factors. Although many inhaled medications are available in aerosol …

Clinical efficacy of vibrating mesh and jet nebulizers with different interfaces in pediatric subjects with asthma

GB Moody, PM Luckett, CM Shockley, R Huang… - Respiratory …, 2020 - rc.rcjournal.com
BACKGROUND: Nebulizers are commonly used in emergency departments to deliver
bronchodilators to children with asthma exacerbations. However, no clinical study …

Guidelines for high‐flow nasal cannula oxygen therapy in neonates (2022)

Y Huang, J Zhao, X Hua, K Luo, Y Shi… - Journal of Evidence …, 2023 - Wiley Online Library
High‐flow nasal cannula (HFNC) oxygen therapy, which is important in noninvasive
respiratory support, is increasingly being used in critically ill neonates with respiratory failure …

[HTML][HTML] A path to successful patient outcomes through aerosol drug delivery to children: A narrative review

A Ari - Annals of translational medicine, 2021 - ncbi.nlm.nih.gov
Although using aerosolized medications is a mainstay of treatment in children with asthma
and other respiratory diseases, there are many issues in terms of device and interface …

Impact of gas humidification and nebulizer position under invasive ventilation: preclinical comparative study of regional aerosol deposition

Y Montigaud, Q Georges, L Leclerc, A Clotagatide… - Scientific Reports, 2023 - nature.com
Successful aerosol therapy in mechanically ventilated patients depends on multiple factors.
Among these, position of nebulizer in ventilator circuit and humidification of inhaled gases …

Mesh nebulizers enabling transnasal pulmonary delivery of medical aerosols to infants and toddlers: Roles, challenges, and opportunities

A Ari, BK Rubin, JB Fink - Frontiers in Drug Delivery, 2022 - frontiersin.org
The development of mesh nebulizer technology has expanded the ability to deliver medical
aerosols to infants and small children via nasal cannula and prongs. Mesh nebulizers do not …