Balance between oxygen transport and blood rheology during resuscitation from hemorrhagic shock with polymerized bovine hemoglobin

AT Williams, A Lucas, CR Muller… - Journal of Applied …, 2020 - journals.physiology.org
Alternatives to blood for use in transfusion medicine have been investigated for decades. An
ideal alternative should improve oxygen (O2)-carrying capacity and O2 delivery and support …

Synthesis and biophysical properties of polymerized human serum albumin

J Elmer, P Cabrales, Q Wang, N Zhang… - Biotechnology …, 2011 - Wiley Online Library
The use of many plasma expanders (PEs) is often limited by undesirable side effects, such
as red blood cell (RBC) aggregation (hydroxyethyl starch), nephrotoxicity (dextran), and …

Tissue Perfusion and Diffusion and Cellular Respiration: Transport and Utilization of Oxygen

CCW Hsia - Seminars in Respiratory and Critical Care …, 2023 - thieme-connect.com
This article provides an overview of the journey of inspired oxygen after its uptake across the
alveolar–capillary interface, and the interplay among tissue perfusion, diffusion, and cellular …

Sodium alginate as viscosity modifier may induce aggregation of red blood cells

L Zhao, G You, F Liao, X Kan, B Wang… - Artificial Cells, Blood …, 2010 - Taylor & Francis
Viscosity of blood substitutes is among the important determinants to restore
microcirculation. Sodium alginate (SA) is always mentioned as “viscosity modifier” in …

PEGylated albumin-heme as an oxygen-carrying plasma expander: Exchange transfusion into acute anemia rat model

Y Huang, T Komatsu, H Yamamoto, H Horinouchi… - Biomaterials, 2006 - Elsevier
Poly (ethylene glycol)(PEG) conjugated recombinant human serum albumin (HSA)
incorporating the synthetic iron-porphyrin (FeP)[PEGylated albumin-heme, PEG (HSA–FeP)] …

Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?

JA Plock, C Contaldo, H Sakai… - American Journal …, 2005 - journals.physiology.org
The aim of this study was to test the influence of hemoglobin, encapsulated in phospholipid
vesicles as an oxygen carrier, given in the course of isovolemic hemodilution to improve …

Small-volume resuscitation from hemorrhagic shock with polymerized human serum albumin

C Messmer, O Yalcin, AF Palmer, P Cabrales - The American journal of …, 2012 - Elsevier
Human serum albumin (HSA) is used as a plasma expander; however, albumin is readily
eliminated from the intravascular space. The objective of this study was to establish the …

Effects of plasma viscosity modulation on cardiac function during moderate hemodilution

S Chatpun, P Cabrales - Asian Journal of Transfusion Science, 2010 - journals.lww.com
Background Previous studies have found that increasing plasma viscosity as whole blood
viscosity decrease has beneficial effects in microvascular hemodynamics. As the heart …

Vasoactive Properties of Keratin‐Derived Compounds

F Nunez, S Trach, L Burnett, R Handa… - …, 2011 - Wiley Online Library
Please cite this paper as: Nunez, Trach, Burnett, Handa, Dyke, Callahan, and Smith (2011).
Vasoactive Properties of Keratin‐Derived Compounds. Microcirculation18 (8), 663–669 …

Low dose nitrite enhances perfusion after fluid resuscitation from hemorrhagic shock

P Cabrales - Resuscitation, 2009 - Elsevier
This study determines the systemic and microvascular hemodynamic consequences of
administering a low dose sodium nitrite after fluid resuscitation from hemorrhagic shock …