[HTML][HTML] Anticoagulants: a short history, their mechanism of action, pharmacology, and indications

M Heestermans, G Poenou, H Hamzeh-Cognasse… - Cells, 2022 - mdpi.com
Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

[HTML][HTML] Control of blood coagulation by hemocompatible material surfaces—a review

J Kuchinka, C Willems, DV Telyshev, T Groth - Bioengineering, 2021 - mdpi.com
Hemocompatibility of biomaterials in contact with the blood of patients is a prerequisite for
the short-and long-term applications of medical devices such as cardiovascular stents …

Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients

B Liu, D Huang, Y Guo, X Sun, C Chen… - CNS neuroscience & …, 2022 - Wiley Online Library
Postoperative neurological disorders, including postoperative delirium (POD), postoperative
cognitive dysfunction (POCD), postoperative covert ischemic stroke, and hemorrhagic …

[HTML][HTML] New perspectives on the effect of dandelion, its food products and other preparations on the cardiovascular system and its diseases

B Olas - Nutrients, 2022 - mdpi.com
Cardiovascular diseases (CVDs) have been the leading cause of death for over 20 years.
The main causative factors are believed to be high cholesterol, obesity, smoking, diabetes …

Contemporary antiplatelet and anticoagulant therapies for secondary stroke prevention: a narrative review of current literature and guidelines

K Bhatia, LM Ladd, KH Carr, M Di Napoli… - Current Neurology and …, 2023 - Springer
Abstract Purpose of Review Stroke is a leading cause of death and disability worldwide. The
annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the …

[HTML][HTML] Direct-acting oral anticoagulants and their reversal agents—an update

SA Kustos, PS Fasinu - Medicines, 2019 - mdpi.com
Background: Over the last ten years, a new class of drugs, known as the direct-acting oral
anticoagulants (DOACs), have emerged at the forefront of anticoagulation therapy. Like the …

Role of direct oral anticoagulants in patients with kidney disease

VK Derebail, MN Rheault, BA Kerlin - Kidney international, 2020 - Elsevier
The anticoagulation field is experiencing a renaissance that began with regulatory approval
of the direct thrombin inhibitor dabigatran, a direct oral anticoagulant (DOAC), in 2010. The …

[HTML][HTML] A review of guidelines on anticoagulation reversal across different clinical scenarios–Is there a general consensus?

TJ Milling, CV Pollack - The American journal of emergency medicine, 2020 - Elsevier
Anticoagulation is key to the treatment/prevention of thromboembolic events. The primary
complication of anticoagulation is serious or life-threatening hemorrhage, which may …

Andexanet alfa for reversal of factor Xa inhibitor-associated anticoagulation

E Carpenter, D Singh, E Dietrich… - … Advances in Drug …, 2019 - journals.sagepub.com
Background: Review of clinical data on andexanet alfa for the reversal of factor Xa (FXa)
inhibitor associated anticoagulation. Data sources: In the present review, we identified …

Studies on Atrial Fibrillation and Venous Thromboembolism in the Past 20 Years: A Bibliometric Analysis Via CiteSpace and VOSviewer

L Miao, J Shi, H Yu, L Song, C Zhu, D Shi… - Journal of the American …, 2023 - Am Heart Assoc
The conjunction of atrial fibrillation (AF) and venous thromboembolism (VTE) is common in
clinical practice. Over the last 2 decades, a significant number of articles (2500) have been …