[PDF][PDF] Protective effects of pioglitazone on cognitive impairment and the underlying mechanisms: A review of literature

A Alhowail, R Alsikhan, M Alsaud… - Drug Design …, 2022 - Taylor & Francis
Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, is
known to have anti-inflammatory and anti-oxidant effects on the brain, and its clinical …

Molecular machinery and pathophysiology of mitochondrial dynamics

YH Chiu, SCA Lin, CH Kuo, CJ Li - Frontiers in Cell and …, 2021 - frontiersin.org
Mitochondria are double-membraned organelles that exhibit fluidity. They are the main site
of cellular aerobic respiration, providing energy for cell proliferation, migration, and survival; …

Luteolin Modulates Neural Stem Cells Fate Determination: In vitro Study on Human Neural Stem Cells, and in vivo Study on LPS-Induced Depression Mice Model

M Achour, F Ferdousi, K Sasaki… - Frontiers in Cell and …, 2021 - frontiersin.org
Luteolin is a natural flavone with neurotrophic effects observed on different neuronal cell
lines. In the present study, we aimed to assess the effect of luteolin on hNSCs fate …

Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation

J Martz, MA Shelton, L Geist, ML Seney… - …, 2023 - nature.com
Maternal immune activation (MIA) puts offspring at greater risk for neurodevelopmental
disorders associated with impaired social behavior. While it is known that immune signaling …

Virus-induced membrane fusion in neurodegenerative disorders

C Osorio, A Sfera, JJ Anton, KG Thomas… - Frontiers in Cellular …, 2022 - frontiersin.org
A growing body of epidemiological and research data has associated neurotropic viruses
with accelerated brain aging and increased risk of neurodegenerative disorders. Many …

Electroacupuncture treatment ameliorates depressive-like behavior and cognitive dysfunction via CB1R dependent mitochondria biogenesis after experimental global …

G Hu, C Zhou, J Wang, X Ma, H Ma, H Yu… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction This study aimed to identify the effect of electroacupuncture (EA) treatment on
post-stroke depression (PSD) and explore whether cannabinoid receptor 1 (CB1R) …

Role of Ca2+/Calmodulin-Dependent Protein Kinase Type II in Mediating Function and Dysfunction at Glutamatergic Synapses

AG Mohanan, S Gunasekaran, RS Jacob… - Frontiers in molecular …, 2022 - frontiersin.org
Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin-
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …

9.4 T static magnetic field ameliorates imatinib mesylate-induced toxicity and depression in mice

X Tian, C Wang, B Yu, Y Fan, L Zhang… - European Journal of …, 2023 - Springer
Purpose 9.4 T magnetic resonance imaging (MRI) has been initially tested on healthy
human volunteers, but its future application will benefit more from experiments with animal …

Knockdown of Amyloid Precursor Protein Increases Ion Channel Expression and Alters Ca2+ Signaling Pathways

M Paschou, D Liaropoulou, V Kalaitzaki… - International Journal of …, 2023 - mdpi.com
Although the physiological role of the full-length Amyloid Precursor Protein (APP) and its
proteolytic fragments remains unclear, they are definitively crucial for normal synaptic …

Fructose Diet-associated molecular alterations in hypothalamus of adolescent rats: a proteomic approach

C D'Ambrosio, L Cigliano, A Mazzoli, M Matuozzo… - Nutrients, 2023 - mdpi.com
Background: The enhanced consumption of fructose as added sugar represents a major
health concern. Due to the complexity and multiplicity of hypothalamic functions, we aim to …