Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

Chronic inflammation is crucial for the pathological process of tumors due to increasing the
infiltration of cytokines, growth factors, and chemokines to the tumor microenvironment …

In recent years, immunotherapy has emerged as a promising strategy for treating solid
tumors, although its efficacy remains limited to a subset of patients. Transforming non …

Background Both inflammatory bowel disease (IBD) and hepato‐pancreato‐biliary cancers
(HPBC) have been established to cause a huge socioeconomic burden. Epidemiological …

Background Pyroptosis is a form of programmed cell death triggered by inflammasomes.
However, the roles of pyroptosis-related genes in thyroid cancer (THCA) remain still unclear …

Immunotherapies represented by programmed cell death protein 1/programmed cell death
ligand 1 (PD‐1/PD‐L1) immune checkpoint inhibitors have made great progress in the field …

Background Pancreatic cancer has a very poor prognosis. Biomarkers that may help predict
or diagnose pancreatic cancer may lead to earlier diagnosis and improved survival …

Pyroptosis, an inflammatory programmed cell death, distinguishes itself from apoptosis and
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …

Across several cancers, IL18 receptor accessory protein (IL18RAP) is abnormally
expressed, and this abnormality is related to tumor immunity and heterogeneous clinical …