Among 65 species belonging to the genus Cornus only two, Cornus mas L. and Cornus
officinalis Sieb. et Zucc.(Cornaceae), have been traditionally used since ancient times …

Despite its broad applications, cisplatin affords considerable nephro-and hepatotoxicity
through triggering inflammatory and oxidative stress cascades. The aim of the current …

Consumers currently demand more nutritious food, which is minimally processed and
naturally produced. Flavonoids are one of the major plant metabolites found throughout the …

Accumulated evidence in epidemiological studies has consistently shown that consumption
of whole grains (WGs) is inversely associated with risk of major chronic diseases such as …

ABSTRACT A multi‐organ‐on‐a‐chip (MOC), also known as a human‐on‐a‐chip, aims to
simulate whole body response to drugs by connecting microscale cell cultures of multiple …

Autophagy is a conserved biological phenomenon that maintains cellular homeostasis
through the clearing of damaged cellular components under cellular stress and offers the …

Estrogen signaling is crucial for breast cancer initiation and progression. Endocrine-based
therapies comprising estrogen receptor (ER) modulators and aromatase inhibitors remain …

In recent years, natural products have increasingly attracted more attention because of their
potential anticancer activity and low intrinsic toxicity. Hispidulin is a natural flavonoid with a …

Gastrointestinal cancers, particularly colorectal cancer, are mainly influenced by the dietary
factor. A diet rich in fruits and vegetables can help to reduce the incidence of colorectal …

Abstract Vernonia amygdalina Delile (Asteraceae) is used in traditional medicine to treat
diabetes mellitus, and some research provides its activity to treat breast cancer. The aim of …