Biological underpinnings for lifelong learning machines

D Kudithipudi, M Aguilar-Simon, J Babb… - Nature Machine …, 2022 - nature.com
Biological organisms learn from interactions with their environment throughout their lifetime.
For artificial systems to successfully act and adapt in the real world, it is desirable to similarly …

[PDF][PDF] Spatial goal coding in the hippocampal formation

N Nyberg, É Duvelle, C Barry, HJ Spiers - Neuron, 2022 - cell.com
The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …

How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

Imagination as a fundamental function of the hippocampus

AE Comrie, LM Frank, K Kay - … Transactions of the …, 2022 - royalsocietypublishing.org
Imagination is a biological function that is vital to human experience and advanced
cognition. Despite this importance, it remains unknown how imagination is realized in the …

The role of the hippocampus in the consolidation of emotional memories during sleep

É Pronier, JF Morici, G Girardeau - Trends in Neurosciences, 2023 - cell.com
Episodic memory relies on the hippocampus, a heterogeneous brain region with distinct
functions. Spatial representations in the dorsal hippocampus (dHPC) are crucial for …

[HTML][HTML] Inhibition allocates spikes during hippocampal ripples

A Noguchi, R Huszár, S Morikawa, G Buzsáki… - Nature …, 2022 - nature.com
Sets of spikes emitted sequentially across neurons constitute fundamental pulse packets in
neural information processing, including offline memory replay during hippocampal sharp …

What neural oscillations can and cannot do for syntactic structure building

N Kazanina, A Tavano - Nature Reviews Neuroscience, 2023 - nature.com
Understanding what someone says requires relating words in a sentence to one another as
instructed by the grammatical rules of a language. In recent years, the neurophysiological …

[HTML][HTML] Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

I Bertocchi, A Eltokhi, A Rozov, VN Chi… - Communications …, 2021 - nature.com
The NMDA receptor-mediated Ca2+ signaling during simultaneous pre-and postsynaptic
activity is critically involved in synaptic plasticity and thus has a key role in the nervous …

How Do You Build a Cognitive Map? The Development of Circuits and Computations for the Representation of Space in the Brain

F Donato, A Xu Schwartzlose… - Annual Review of …, 2023 - annualreviews.org
In mammals, the activity of neurons in the entorhinal-hippocampal network is modulated by
the animal's position and its movement through space. At multiple stages of this distributed …

Maladaptive explore/exploit trade-offs in schizophrenia

LJ Speers, DK Bilkey - Trends in Neurosciences, 2023 - cell.com
Schizophrenia is a complex disorder that remains poorly understood, particularly at the
systems level. In this opinion article we argue that the explore/exploit trade-off concept …