[HTML][HTML] Molecular mechanisms of human hypertension

RP Lifton, AG Gharavi, DS Geller - Cell, 2001 - cell.com
Hypertension, or elevated arterial blood pressure, is a been operationally defined as the
blood pressure level substantial public health problem, affecting 25% of the above which …

Pathogenesis of hypertension

S Oparil, MA Zaman, DA Calhoun - Annals of internal medicine, 2003 - acpjournals.org
Increased recognition of specific causes of hypertension may lead to therapies that address
specific pathophysiologic mechanisms and cause fewer adverse effects. Research to …

Sex-specific genetic architecture of human disease

C Ober, DA Loisel, Y Gilad - Nature Reviews Genetics, 2008 - nature.com
Sexual dimorphism in anatomical, physiological and behavioural traits are characteristics of
many vertebrate species. In humans, sexual dimorphism is also observed in the prevalence …

[图书][B] Генетический паспорт–основа индивидуальной и предиктивной медицины

В Баранов - 2022 - books.google.com
В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

Renin angiotensin system and gender differences in the cardiovascular system

M Fischer, A Baessler, H Schunkert - Cardiovascular research, 2002 - academic.oup.com
In the effort to explain gender-related differences of the cardiovascular system, the renin–
angiotensin system experienced intensive exploration. Indeed, the development of …

Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the …

CJ O'Donnell, K Lindpaintner, MG Larson, VS Rao… - Circulation, 1998 - Am Heart Assoc
Background—There is controversy regarding the association of the angiotensin-converting
enzyme deletion-insertion (ACE D/I) polymorphism with systemic hypertension and with …

Animal models of hypertension: an overview

LO Lerman, AR Chade, V Sica, C Napoli - Journal of Laboratory and …, 2005 - Elsevier
Hypertension is a multifactorial disease involving complex interactions between genetic and
environmental factors. Development of experimental models of hypertension allowed …

[HTML][HTML] Linkage and association analysis of angiotensin I–converting enzyme (ACE)–gene polymorphisms with ACE concentration and blood pressure

X Zhu, N Bouzekri, L Southam, RS Cooper… - The American Journal of …, 2001 - cell.com
Considerable effort has been expended to determine whether the gene for angiotensin I–
converting enzyme (ACE) confers susceptibility to cardiovascular disease. In this study, we …

Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men: the Suita Study

J Higaki, S Baba, T Katsuya, N Sato, K Ishikawa… - Circulation, 2000 - Am Heart Assoc
Background—The Framingham Study recently revealed that the homozygous deletion
polymorphism of the angiotensin-converting enzyme gene (ACE DD) is associated with …

Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on …

DK Arnett, AE Baird, RA Barkley, CT Basson… - Circulation, 2007 - Am Heart Assoc
Atherosclerotic cardiovascular disease (CVD) is a major health problem in the United States
and around the world. Evidence accumulated over decades convincingly demonstrates that …