Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning

G Heusch - Circulation research, 2015 - Am Heart Assoc
Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

[HTML][HTML] Anti-apoptosis and cell survival: a review

L Portt, G Norman, C Clapp, M Greenwood… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Type I programmed cell death (PCD) or apoptosis is critical for cellular self-destruction for a
variety of processes such as development or the prevention of oncogenic transformation …

Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training

AL Baggish, A Hale, RB Weiner… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary MicroRNA (miRNA) molecules are essential intracellular mediators
of numerous biological processes including angiogenesis, inflammation, and mitochondrial …

Exosomal circHIPK3 released from hypoxia‐pretreated cardiomyocytes regulates oxidative damage in cardiac microvascular endothelial cells via the miR‐29a/IGF‐1 …

Y Wang, R Zhao, W Liu, Z Wang, J Rong… - Oxidative medicine …, 2019 - Wiley Online Library
Background/Aims. Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs
that regulate gene expression in eukaryotes. Recently, exosomes from cardiomyocytes …

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

AB Aurora, AI Mahmoud, X Luo… - The Journal of …, 2012 - Am Soc Clin Investig
Early reperfusion of ischemic cardiac tissue remains the most effective intervention for
improving clinical outcome following myocardial infarction. However, abnormal increases in …

Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells

KM Luther, L Haar, M McGuinness, Y Wang… - Journal of molecular and …, 2018 - Elsevier
Though experimental, stem cell transplantation has the potential to improve the condition of
the heart after myocardial infarction. It does so by reducing infarct size and inducing repair of …

Smartphone fluorescence spectroscopy

H Yu, Y Tan, BT Cunningham - Analytical chemistry, 2014 - ACS Publications
We demonstrate the first use of smartphone spectrophotometry for readout of fluorescence-
based biological assays. We evaluated the smartphone fluorimeter in the context of a …

miR-21 in human cardiomyopathies

Surina, RA Fontanella, L Scisciola… - Frontiers in …, 2021 - frontiersin.org
miR-21 is a 22-nucleotide long microRNA that matches target mRNAs in a complementary
base pairing fashion and regulates gene expression by repressing or degrading target …

Hypoxia: a master regulator of microRNA biogenesis and activity

S Nallamshetty, SY Chan, J Loscalzo - Free Radical Biology and Medicine, 2013 - Elsevier
Hypoxia, or low oxygen tension, is a unique environmental stress that induces global
changes in a complex regulatory network of transcription factors and signaling proteins to …