Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …

Systemic sclerosis (SSc) is an autoimmune disease with a poor prognosis. To date, the
pathogenesis of SSc is still unclear; moreover, its pathological conditions include …

Autoimmune diseases are a group of serious immune system disorders that are usually
idiopathic and persistent. Currently, autoimmune diseases are often diagnosed after obvious …

Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract
responsible for intestinal lesions. The multifactorial etiology attributed to CD includes a …

In immunology, the discovery of regulatory T (Treg) cells was a major breakthrough. Treg
cells play a key role in pregnancy maintenance, in the prevention of autoimmune responses …

Periodontitis is one of the most common oral diseases worldwide, and it is associated with
various systemic diseases, including cognitive diseases. STAT3 regulates the inflammatory …

Abrupt onset of severe neuropsychiatric symptoms including obsessive–compulsive
disorder, tics, anxiety, mood swings, irritability, and restricted eating is described in children …

Objective Graves' disease (GD) is one of the most common autoimmune conditions, but the
mechanisms underlying the associated induction of autoimmunity are not known. We …

The phenotypic and functional complexities of T cells engender complicated and often
confusing concepts as to how T cells ignite, accelerate and brake the inflammatory …

This study investigated the role of IL-35 in systemic sclerosis (SSc) patients, focusing on
CD4+ T cell response and immunomodulatory cytokine production. By comparing the …