This review critically appraises the published microbiologic and clinical data on the
treatment of patients with carbapenem‐resistant Acinetobacter baumannii infections …

This study aimed to determine the proportion of heteroresistance in carbapenem-resistant
Acinetobacter calcoaceticus-baumannii complex (CRAB) isolates in the cefiderocol arm of …

Cefiderocol is a novel siderophore cephalosporin that forms a complex with extracellular
free ferric iron, which leads to transportation across the outer cell membrane to exert its …

Background As cefiderocol is increasingly being prescribed in clinical practice, it is critical
that we understand key mechanisms contributing to acquired resistance to this agent …

Objectives Contezolid is a novel oxazolidinone antibacterial agent for managing infections
caused by aerobic and anaerobic Gram-positive bacteria including methicillin-resistant …

Antibiotics underpin the 'modern medicine'that has increased life expectancy, leading to
societies with sizeable vulnerable elderly populations who have suffered disproportionately …

The purpose of this narrative review is to bring together the most recent epidemiologic,
preclinical, and clinical findings to offer our perspective on best practices for managing …

Cefiderocol is an option for infections caused by multidrug-resistant Pseudomonas
aeruginosa, but its in vitro activity against these isolates and its clinical effectiveness for …

Gram-negative bacterial resistance to antimicrobials has had an exponential increase at a
global level during the last decades and represent an everyday challenge, especially for the …

The diagnosis and treatment of urinary tract infections (UTIs) remain challenging due to the
lack of convenient assessment techniques and to the resistance to conventional …