As a multitargeted kinase inhibitor, sunitinib has carved its way into demonstrating itself as a
most effective tyrosine kinase inhibitor in the treatment of metastatic renal cell carcinoma …

Cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC)(resection of the
primary tumor for debulking purposes) was considered to be an important part of oncological …

Background Clear cell renal cell carcinoma (ccRCC) is common in urinary system tumors.
Cuproptosis is a non-apoptotic cell death pathway. Copper binds to fatty acylated …

Aim: Real life data on the clinical correlates and prognostic value of metastatic sites in
metastatic renal cell carcinoma (RCC) are needed. This parameter was assessed in RCC …

A growing body of evidence shows that vasculogenic mimicry (VM) is closely related to the
invasion and metastasis of many tumor cells. Although the estrogen receptor (ER) can …

Background. The aim of this systematic evaluation and meta‐analysis was to analyze the
efficacy and adverse effects of adjuvant targeted therapy regimens in advanced or …

Background. Sunitinib is a standard treatment for metastatic clear cell renal cell carcinoma
(mccRCC). Data on its activity in the rare variant of metastatic chromophobe renal cell …

Non-clear cell renal cell carcinomas (nccRCCs) are a heterogeneous group of tumors,
characterized by different histological features, molecular alterations, clinical outcomes, and …

Introduction Local control in sarcoma is rarely achieved with exclusive radiotherapy (RT).
We aim to assess the feasibility and safety of sunitinib continuously administrated with …

Background: This study aims to tackle the impact of histological subtype on the presentation
and treatment trends of renal cell carcinoma (RCC). Methods: RCC cases, diagnosed from …