Biological activity of algal derived carrageenan: A comprehensive review in light of human health and disease

B Pradhan, JS Ki - International Journal of Biological Macromolecules, 2023 - Elsevier
Carrageenans are a family of natural linear sulfated polysaccharides derived from red
seaweeds and used as a common food additive. Carrageenan's properties, impact on …

[HTML][HTML] Algal phlorotannins as novel antibacterial agents with reference to the antioxidant modulation: Current advances and future directions

B Pradhan, R Nayak, PP Bhuyan, S Patra, C Behera… - Marine Drugs, 2022 - mdpi.com
The increasing drug resistance of infectious microorganisms is considered a primary
concern of global health care. The screening and identification of natural compounds with …

[HTML][HTML] Toxic effects and tumor promotion activity of marine phytoplankton toxins: A review

B Pradhan, H Kim, S Abassi, JS Ki - Toxins, 2022 - mdpi.com
Phytoplankton are photosynthetic microorganisms in aquatic environments that produce
many bioactive substances. However, some of them are toxic to aquatic organisms via filter …

Antioxidant and chemotherapeutic efficacies of seaweed‐derived phlorotannins in cancer treatment: a review regarding novel anticancer drugs

B Pradhan, JS Ki - Phytotherapy Research, 2023 - Wiley Online Library
The ineffectiveness of traditional cancer therapies due to drug resistance, nontargeted
delivery, and chemotherapy‐associated adverse side effects has shifted attention to …

Immunomodulatory and anti-inflammatory and anticancer activities of porphyran, a sulfated galactan

B Pradhan, L Rout, JS Ki - Carbohydrate Polymers, 2023 - Elsevier
Seaweeds are high in bioactive chemicals frequently used to treat human illnesses.
Porphyran is a polysaccharide found in the red seaweeds of the genus Porphyra. Porphyran …

[HTML][HTML] 20-Hydroxyecdysone Confers Antioxidant and Antineoplastic Properties in Human Non-Small Cell Lung Cancer Cells

O Shuvalov, Y Kirdeeva, E Fefilova, S Netsvetay… - Metabolites, 2023 - mdpi.com
20-Hydroxyecdysone (20E) is an arthropod hormone which is synthesized by some plants
as part of their defense mechanism. In humans, 20E has no hormonal activity but possesses …

[HTML][HTML] Cleistocalyx nervosum var. paniala Berry Promotes Antioxidant Response and Suppresses Glutamate-Induced Cell Death via SIRT1/Nrf2 Survival Pathway …

W Nantacharoen, SJ Baek, W Plaingam… - Molecules, 2022 - mdpi.com
Excessive glutamate neurotransmitters result in oxidative neurotoxicity, similar to
neurodegeneration. An indigenous berry of Thailand, Cleistocalyx nervosum var. paniala …

[HTML][HTML] Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic …

R Huber, A Koval, L Marcourt, M Héritier… - Frontiers in …, 2022 - frontiersin.org
The Wnt signaling pathway controls multiple events during embryonic development of
multicellular animals and is carcinogenic when aberrantly activated in adults. Breast cancer …

[HTML][HTML] The anticancer potential of plant-derived nutraceuticals via the modulation of gene expression

M Vrânceanu, D Galimberti, R Banc, O Dragoş… - Plants, 2022 - mdpi.com
Current studies show that approximately one-third of all cancer-related deaths are linked to
diet and several cancer forms are preventable with balanced nutrition, due to dietary …

[HTML][HTML] An insight into neuropeptides inhibitors in the biology of colorectal cancer: Opportunity and translational perspectives

A Srivastava, D Rikhari, B Pradhan, KK Bharadwaj… - Applied Sciences, 2022 - mdpi.com
Neuropeptides are mainly secreted from the human central and peripheral nervous systems.
Neuropeptides bind to its cognate rhodopsin-like G-protein coupled receptor (GPCR) and …