[HTML][HTML] Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis

SA Buckley, BL Wood, M Othus, CS Hourigan… - …, 2017 - ncbi.nlm.nih.gov
Minimal residual disease prior to allogeneic hematopoietic cell transplantation has been
associated with increased risk of relapse and death in patients with acute myeloid leukemia …

Minimal residual disease in acute myeloid leukaemia

CS Hourigan, JE Karp - Nature reviews Clinical oncology, 2013 - nature.com
Technological advances in the laboratory have led to substantial improvements in clinical
decision making through the introduction of pretreatment prognostic risk stratification factors …

Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia

N Gökbuget, H Dombret, M Bonifacio… - Blood, The Journal …, 2018 - ashpublications.org
Abstract Approximately 30% to 50% of adults with acute lymphoblastic leukemia (ALL) in
hematologic complete remission after multiagent therapy exhibit minimal residual disease …

Allogeneic hematopoietic cell transplantation for acute myeloid leukemia: time to move toward a minimal residual disease–based definition of complete remission?

D Araki, BL Wood, M Othus, JP Radich… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Patients with acute myeloid leukemia (AML) who are in morphologic complete
remission are typically considered separately from patients with active disease (ie,≥ 5 …

Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia

JM Klco, CA Miller, M Griffith, A Petti, DH Spencer… - Jama, 2015 - jamanetwork.com
Importance Tests that predict outcomes for patients with acute myeloid leukemia (AML) are
imprecise, especially for those with intermediate risk AML. Objectives To determine whether …

Postinduction Minimal Residual Disease Predicts Outcome and Benefit From Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia With NPM1 Mutation …

M Balsat, A Renneville, X Thomas… - Journal of Clinical …, 2017 - ascopubs.org
Purpose This study assessed the prognostic impact of postinduction NPM1-mutated (NPM1
m) minimal residual disease (MRD) in young adult patients (age, 18 to 60 years) with acute …

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

OA Guryanova, K Shank, B Spitzer, L Luciani… - Nature medicine, 2016 - nature.com
Although the majority of patients with acute myeloid leukemia (AML) initially respond to
chemotherapy, many of them subsequently relapse, and the mechanistic basis for AML …

Prognostic relevance of treatment response measured by flow cytometric residual disease detection in older patients with acute myeloid leukemia

SD Freeman, P Virgo, S Couzens… - Journal of Clinical …, 2013 - ascopubs.org
Purpose Older patients with acute myeloid leukemia (AML) have a high relapse rate after
standard chemotherapy. We investigated whether measuring chemotherapy sensitivity by …

Comparison of minimal residual disease as outcome predictor for AML patients in first complete remission undergoing myeloablative or nonmyeloablative allogeneic …

RB Walter, B Gyurkocza, BE Storer, CD Godwin… - Leukemia, 2015 - nature.com
Minimal residual disease (MRD) is associated with adverse outcome in acute myeloid
leukemia (AML) after myeloablative (MA) hematopoietic cell transplantation (HCT). We …

Measurable residual disease, conditioning regimen intensity, and age predict outcome of allogeneic hematopoietic cell transplantation for acute myeloid leukemia in …

MH Gilleece, M Labopin, I Yakoub‐Agha… - American journal of …, 2018 - Wiley Online Library
Patients with acute myeloid leukemia (AML) in morphological first complete remission (CR1)
pre‐allogeneic hematopoietic cell transplantation (HCT) may have measurable residual …