Means, mechanisms and consequences of adenine methylation in DNA
K Boulias, EL Greer - Nature Reviews Genetics, 2022 - nature.com
Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …
Homeodomain proteins: an update
TR Bürglin, M Affolter - Chromosoma, 2016 - Springer
Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …
The role of mutations in epigenetic regulators in myeloid malignancies
AH Shih, O Abdel-Wahab, JP Patel… - Nature Reviews Cancer, 2012 - nature.com
Recent genomic studies have identified novel recurrent somatic mutations in patients with
myeloid malignancies, including myeloproliferative neoplasms (MPNs), myelodysplastic …
myeloid malignancies, including myeloproliferative neoplasms (MPNs), myelodysplastic …
[HTML][HTML] ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
Recurrent somatic ASXL1 mutations occur in patients with myelodysplastic syndrome,
myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with …
myeloproliferative neoplasms, and acute myeloid leukemia, and are associated with …
Plant GATA factors: their biology, phylogeny, and phylogenomics
C Schwechheimer, PM Schröder… - Annual review of plant …, 2022 - annualreviews.org
GATA factors are evolutionarily conserved transcription factors that are found in animals,
fungi, and plants. Compared to that of animals, the size of the plant GATA family is …
fungi, and plants. Compared to that of animals, the size of the plant GATA family is …
Polymorphic toxin systems: comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative …
Background Proteinaceous toxins are observed across all levels of inter-organismal and
intra-genomic conflicts. These include recently discovered prokaryotic polymorphic toxin …
intra-genomic conflicts. These include recently discovered prokaryotic polymorphic toxin …
Molecular architecture of polycomb repressive complexes
EC Chittock, S Latwiel, TCR Miller… - Biochemical Society …, 2017 - portlandpress.com
The polycomb group (PcG) proteins are a large and diverse family that epigenetically
repress the transcription of key developmental genes. They form three broad groups of …
repress the transcription of key developmental genes. They form three broad groups of …
Surveillance recommendations for children with overgrowth syndromes and predisposition to Wilms tumors and hepatoblastoma
JM Kalish, L Doros, LJ Helman, RC Hennekam… - Clinical Cancer …, 2017 - AACR
A number of genetic syndromes have been linked to increased risk for Wilms tumor (WT),
hepatoblastoma (HB), and other embryonal tumors. Here, we outline these rare syndromes …
hepatoblastoma (HB), and other embryonal tumors. Here, we outline these rare syndromes …
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
V Gelsi-Boyer, M Brecqueville, R Devillier… - Journal of hematology & …, 2012 - Springer
The ASXL1 gene is one of the most frequently mutated genes in malignant myeloid
diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic …
diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic …
An adversarial DNA N6-methyladenine-sensor network preserves polycomb silencing
SM Kweon, Y Chen, E Moon, K Kvederaviciutė… - Molecular cell, 2019 - cell.com
Adenine N6 methylation in DNA (6mA) is widespread among bacteria and phage and is
detected in mammalian genomes, where its function is largely unexplored. Here we show …
detected in mammalian genomes, where its function is largely unexplored. Here we show …