Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

In the face of an “epidemic” increase in myopia over the last decades and myopia
prevalence predicted to reach 2.5 billion people by the end of this decade, there is an urgent …

Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs, with five
subtypes named M1–M5) are a unique subclass of RGCs with axons that project directly to …

Image-and non-image-forming vision are essential for animal behavior. Here we use
genetically modified mouse lines to examine retinal circuits driving image-and non-image …

In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …

During mouse postnatal eye development, the embryonic hyaloid vascular network
regresses from the vitreous as an adaption for high-acuity vision. This process occurs with …

The mammalian retina is the most unique tissue among those that display robust
circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light …

The ON pathway mutation in nob mice is associated with altered refractive development,
and an increased susceptibility to form-deprivation (FD) myopia. In this study, we used …

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are the most recently discovered
photoreceptor class in the human retina. This Element integrates new knowledge and …