The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function
Y Zhao, M Jia, W Chen, Z Liu - Free Radical Biology and Medicine, 2022 - Elsevier
Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …
Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative …
It remains essential to decipher some of the pathological mechanisms that link obesity with
deteriorating human health. Insulin resistance, due to enhanced free fatty acid substrate …
deteriorating human health. Insulin resistance, due to enhanced free fatty acid substrate …
Muscle‐specific changes in protein synthesis with aging and reloading after disuse atrophy
Background Successful strategies to halt or reverse sarcopenia require a basic
understanding of the factors that cause muscle loss with age. Acute periods of muscle loss in …
understanding of the factors that cause muscle loss with age. Acute periods of muscle loss in …
[HTML][HTML] Short-term high-fat feeding does not alter mitochondrial lipid respiratory capacity but triggers mitophagy response in skeletal muscle of mice
SE Ehrlicher, HD Stierwalt, SA Newsom… - Frontiers in …, 2021 - frontiersin.org
Lipid overload of the mitochondria is linked to the development of insulin resistance in
skeletal muscle which may be a contributing factor to the progression of type 2 diabetes …
skeletal muscle which may be a contributing factor to the progression of type 2 diabetes …
Two weeks of high-intensity interval training increases skeletal muscle mitochondrial respiration via complex-specific remodeling in sedentary humans
PM Batterson, EM McGowan… - Journal of applied …, 2023 - journals.physiology.org
Aerobic training remodels the quantity and quality (function per unit) of skeletal muscle
mitochondria to promote substrate oxidation, however, there remain key gaps in …
mitochondria to promote substrate oxidation, however, there remain key gaps in …
Robust intrinsic differences in mitochondrial respiration and H2O2 emission between L6 and C2C12 cells
MM Robinson, BK Sather, ER Burney… - … of Physiology-Cell …, 2019 - journals.physiology.org
Rat L6 and mouse C2C12 cell lines are commonly used to investigate myocellular
metabolism. Mitochondrial characteristics of these cell lines remain poorly understood …
metabolism. Mitochondrial characteristics of these cell lines remain poorly understood …
[HTML][HTML] Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in mice fed a high-fat …
Obesity is often accompanied by heightened circulating and tissue inflammation along with
an increase in sphingolipids (eg, ceramides) in metabolically active and insulin-sensitive …
an increase in sphingolipids (eg, ceramides) in metabolically active and insulin-sensitive …
A genetically heterogeneous rat model with divergent mitochondrial genomes
R Sathiaseelan, B Ahn, MB Stout… - The Journals of …, 2023 - academic.oup.com
We generated a genetically heterogenous rat model by a 4-way cross strategy using 4
inbred strains (Brown Norway [BN], Fischer 344 [F344], Lewis [LEW], and Wistar Kyoto [KY]) …
inbred strains (Brown Norway [BN], Fischer 344 [F344], Lewis [LEW], and Wistar Kyoto [KY]) …
[HTML][HTML] Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation
SE Ehrlicher, HD Stierwalt, BF Miller… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
Understanding the mechanisms regulating mitochondrial respiratory function and
adaptations to metabolic challenges, such as exercise and high dietary fat, is necessary to …
adaptations to metabolic challenges, such as exercise and high dietary fat, is necessary to …
Proteomics Analysis of Skeletal Muscle from Leptin‐Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition
M Schönke, M Björnholm, AV Chibalin, JR Zierath… - …, 2018 - Wiley Online Library
Skeletal muscle insulin resistance, an early metabolic defect in the pathogenesis of type 2
diabetes (T2D), may be a cause or consequence of altered protein expression profiles …
diabetes (T2D), may be a cause or consequence of altered protein expression profiles …