The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases

M Piotrowska, M Swierczynski, J Fichna… - Pharmacological …, 2021 - Elsevier
Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

[HTML][HTML] The role of Nrf2 in the pathogenesis and treatment of ulcerative colitis

S Peng, L Shen, X Yu, L Zhang, K Xu, Y Xia… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory bowel disease involving mainly the
colorectal mucosa and submucosa, the incidence of which has been on the rise in recent …

Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway

T Xiong, X Zheng, K Zhang, H Wu, Y Dong… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Ulcerative colitis (UC) is a chronic inflammatory bowel
disease (IBD), that is associated with a significantly increased risk of colon cancer. As a …

Salvia miltiorrhiza polysaccharide and its related metabolite 5-methoxyindole-3-carboxaldehyde ameliorate experimental colitis by regulating Nrf2/Keap1 signaling …

YP Fu, X Peng, CW Zhang, QX Jiang, CY Li… - Carbohydrate …, 2023 - Elsevier
The roots of Salvia miltiorrhiza have been used in Traditional Chinese Medicine for
thousands of years. However, tons of aerial parts of this plant are usually discarded in the …

Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1–Nrf2 Signaling Pathway and Regulating Gut Microbiota

W Yang, Z Huang, H Xiong, J Wang… - Journal of Agricultural …, 2022 - ACS Publications
Inflammatory bowel disease (IBD), with increasing incidence, causes a range of
gastrointestinal symptoms and brings distress and impact on the health and lives of patients …

Anneslea fragrans Wall. ameliorates ulcerative colitis via inhibiting NF-κB and MAPK activation and mediating intestinal barrier integrity

X Deng, Y Wang, L Tian, M Yang, S He, Y Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Anneslea fragrans Wall. is traditionally used as a
folk medicine in treating indigestion, fever, dysentery, diarrhea, and liver inflammation in …

[HTML][HTML] Effects of dietary polyherbal mixtures on growth performance, antioxidant capacity, immune function and jejunal health of yellow-feathered broilers

M Liu, J Zhou, Y Li, Y Ding, J Lian, Q Dong, Q Qu, W Lv… - Poultry science, 2023 - Elsevier
This study aimed to investigate the effects of polyherbal mixtures (PHM) on growth
performance, antioxidant capacities, immune function, and intestinal health in yellow …

Kuijieling decoction suppresses NLRP3-Mediated pyroptosis to alleviate inflammation and experimental colitis in vivo and in vitro

F Jie, S Xiao, Y Qiao, Y You, Y Feng, Y Long… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Ulcerative colitis (UC) is an autoimmune disease.
Although the mortality rate of UC is not very high, it has a considerable morbidity rate and an …

[HTML][HTML] Gut Microbiota: The Potential Key Target of TCM's Therapeutic Effect of Treating Different Diseases Using the Same Method—UC and T2DM as Examples

B Zhang, K Liu, H Yang, Z Jin, Q Ding… - Frontiers in Cellular and …, 2022 - frontiersin.org
Traditional Chinese herbal medicine often exerts the therapeutic effect of “treating different
diseases with the same method” in clinical practice; in other words, it is a kind of herbal …

[HTML][HTML] Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment

S Yuan, Q Wang, J Li, JC Xue, Y Li, H Meng, XT Hou… - Chinese Medicine, 2022 - Springer
Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the
intestine, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and …