Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Updated assessment of the prevalence, spectrum and case definition of autoimmune disease

SM Hayter, MC Cook - Autoimmunity reviews, 2012 - Elsevier
Autoimmune diseases are heterogeneous with regard to prevalence, manifestations, and
pathogenesis. The classification of autoimmune diseases has varied over time. Here, we …

Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel …

FW Miller, L Alfredsson, KH Costenbader… - Journal of …, 2012 - Elsevier
Autoimmune diseases (AID) are a collection of many complex disorders of unknown etiology
resulting in immune responses to self-antigens and are thought to result from interactions …

The antiphospholipid syndrome in patients with systemic lupus erythematosus

GJ Pons-Estel, L Andreoli, F Scanzi, R Cervera… - Journal of …, 2017 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
occurrence of venous and/or arterial thrombosis and pregnancy morbidity in the presence of …

Inflammation-induced thrombosis: mechanisms, disease associations and management

K Aksu, A Donmez, G Keser - Current pharmaceutical design, 2012 - ingentaconnect.com
Although inflammation-induced thrombosis is a well-known entity, its pathogenesis remains
complicated. There are complex interactions between inflammation and hemostasis …

The autoimmune bases of infertility and pregnancy loss

HJA Carp, C Selmi, Y Shoenfeld - Journal of autoimmunity, 2012 - Elsevier
Several lines of evidence suggest that autoimmune mechanisms may influence the
reproductive life and fertility of both sexes, commonly manifesting as infertility or pregnancy …

Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events

K Otomo, T Atsumi, O Amengual, Y Fujieda… - Arthritis & …, 2012 - Wiley Online Library
Objective To define the antiphospholipid score (aPL‐S) by testing multiple antiphospholipid
antibodies (aPL) and to evaluate its efficacy for the diagnosis of antiphospholipid syndrome …

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia
characterized by recurrent thrombosis and pregnancy morbidity in the presence of …

The significance of autoantibodies against β2-glycoprotein I

PG de Groot, RT Urbanus - Blood, The Journal of the American …, 2012 - ashpublications.org
The antiphospholipid syndrome (APS) is defined by the persistent presence of
antiphospholipid antibodies in patients with a history of thrombosis and/or pregnancy …

The treatment of anti-phospholipid syndrome: a comprehensive clinical approach

CB Chighizola, L Andreoli, M Gerosa, A Tincani… - Journal of …, 2018 - Elsevier
Anti-phospholipid syndrome (APS) is an acquired pro-thrombotic autoimmune disease that
predisposes to thrombotic events and/or obstetric complications, in the persistent presence …