[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications

D De Ridder, D Adhia, S Vanneste - Neuroscience & Biobehavioral …, 2021 - Elsevier
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Brain circuits for pain and its treatment

N Mercer Lindsay, C Chen, G Gilam… - Science translational …, 2021 - science.org
Pain is a multidimensional experience with sensory-discriminative, affective-motivational,
and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering …

Chronic pain: structural and functional changes in brain structures and associated negative affective states

S Yang, MC Chang - International journal of molecular sciences, 2019 - mdpi.com
Chronic pain is a condition in which pain progresses from an acute to chronic state and
persists beyond the healing process. Chronic pain impairs function and decreases patients' …

Common and stimulus-type-specific brain representations of negative affect

M Čeko, PA Kragel, CW Woo, M López-Solà… - Nature …, 2022 - nature.com
The brain contains both generalized and stimulus-type-specific representations of aversive
events, but models of how these are integrated and related to subjective experience are …

Cognitive and emotional control of pain and its disruption in chronic pain

MC Bushnell, M Čeko, LA Low - Nature reviews neuroscience, 2013 - nature.com
Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Mindfulness meditation–based pain relief: a mechanistic account

F Zeidan, DR Vago - Annals of the New York Academy of …, 2016 - Wiley Online Library
Pain is a multidimensional experience that involves interacting sensory, cognitive, and
affective factors, rendering the treatment of chronic pain challenging and financially …

Reward and motivation in pain and pain relief

E Navratilova, F Porreca - Nature neuroscience, 2014 - nature.com
Pain is fundamentally unpleasant, a feature that protects the organism by promoting
motivation and learning. Relief of aversive states, including pain, is rewarding. The …

Brain mechanisms supporting the modulation of pain by mindfulness meditation

F Zeidan, KT Martucci, RA Kraft, NS Gordon… - Journal of …, 2011 - Soc Neuroscience
The subjective experience of one's environment is constructed by interactions among
sensory, cognitive, and affective processes. For centuries, meditation has been thought to …

Virtual reality and pain management: current trends and future directions

A Li, Z Montaño, VJ Chen, JI Gold - Pain management, 2011 - Taylor & Francis
Virtual reality (VR) has been used to manage pain and distress associated with a wide
variety of known painful medical procedures. In clinical settings and experimental studies …

The influence of negative emotions on pain: behavioral effects and neural mechanisms

K Wiech, I Tracey - Neuroimage, 2009 - Elsevier
The idea that pain can lead to feelings of frustration, worry, anxiety and depression seems
obvious, particularly if it is of a chronic nature. However, there is also evidence for the …