A protein (Mr= 63,000) from calf serum that promotes the pigmentation of cultured chick
neural crest and mouse melanoma cells has been partially isolated and characterized in this …

Abstract The synthesis of 131 I-5-iodo-2-thiouracils by electrophilic iodination or by an
electrophilic isotopic exchange using chloramine-T and Iodo-gen TM has been investigated …

Short-term synthesis of radioactivity labeled melanin (using dl-[2-14 C] tyrosine or 2-[2-14 C]
thiouracil) by chick retinal pigment tissues in vitro was not influenced by inhibitors of protein …

Abstract The incorporation of [2-14C]-2-thiouracil and a series of [125I]-5-iodo-2-thiouracils
([125I] ISUra (s)) into cultured Greene hamster melanoma cells was determined in order to …

Electron microscopic autoradiography was used to investigate the relationship between
melanin formation and thiol incorporation in premelanosomes of genetically defined chick …

We cloned the complete cDNA of methionine rich hexamerin from rice moth, Corcyra
cephalonica using RACE strategy. The amplicon size was 2.5 kb with an ORF of 2.31 kb …

Thiouracil (TU) selectively binds to the pigment melanin during melanogenesis and is
rapidly cleared from normal tissues. This compound shows little affinity for pre-formed …

Iodo-2-thiouracil (ITU) is of interest due to its ability to bind specifically to the pigment
melanin during melanogenesis and is of potential value in the diagnosis and treatment of …

Abstract [123I]-5-iodo-2-thiouracil (123I-ITU) was evaluated as a radiopharmaceutical for
tumor detection in 10 patients with proven choroidal melanoma. Uptake of 123I-ITU was …

The uptake and retention of 14 C-thiouracil and 125 I-thiouracil in small lung metastases of
B16 murine melanoma was studied in beige mice injected intravenously with melanoma …