Cerebral protection by remote ischemic post-conditioning in patients with ischemic stroke: a systematic review and meta-analysis of randomized controlled trials

M Lu, Y Wang, X Yin, Y Li, H Li - Frontiers in Neurology, 2022 - frontiersin.org
Background There is evidence that remote limb ischemic postconditioning (RIPostC) can
reduce ischemia-reperfusion injury (IRI) and improve the prognosis of patients with ischemic …

Role of microglia in stroke

AM Planas - Glia, 2024 - Wiley Online Library
Microglia play key roles in the post‐ischemic inflammatory response and damaged tissue
removal reacting rapidly to the disturbances caused by ischemia and working to restore the …

MLIF modulates microglia polarization in ischemic stroke by targeting eEF1A1

Y Liu, S Deng, Z Song, Q Zhang, Y Guo, Y Yu… - Frontiers in …, 2021 - frontiersin.org
Monocyte locomotion inhibitory factor (MLIF) is a heat-stable pentapeptide from Entamoeba
histolytica. Our previous study found that MLIF protects against ischemic stroke in rats and …

Tumor necrosis factor (TNF)-α-stimulated gene 6 (TSG-6): A promising immunomodulatory target in acute neurodegenerative diseases

D La Russa, C Di Santo, I Lizasoain, A Moraga… - International Journal of …, 2023 - mdpi.com
Tumor necrosis factor (TNF)-α-stimulated gene 6 (TSG-6), the first soluble chemokine-
binding protein to be identified in mammals, inhibits chemotaxis and transendothelial …

Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition

L Huang, Y Zhang, Y Liu, Z Liang, J Chen… - ACS Chemical …, 2024 - ACS Publications
Neuronal death resulting from ischemic stroke is the primary cause of adult mortality and
disability, and effective neuroprotective agents for poststroke intervention are still lacking …

Remote Ischemia Postconditioning Mitigates Hippocampal Neuron Impairment by Modulating Cav1. 2-CaMKIIα-Aromatase Signaling After Global Cerebral Ischemia …

L Wang, F Gao, L Chen, W Sun, H Liu, W Yang… - Molecular …, 2024 - Springer
Abstract Brain-derived estrogen (BDE2) is gaining attention as an endogenous
neurotransmitter. Recent research has revealed that selectively removing the aromatase …

Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke

L Yu, Z Zhang, H Chen, M Wang, W Mao… - Bioengineering & …, 2023 - Wiley Online Library
The repetitive inflation–deflation of a blood pressure cuff on a limb is known as remote limb
ischemic postconditioning (RIPostC). It prevents brain damage induced by acute ischemia …

Characterization of the Involvement of Tumour Necrosis Factor (TNF)-α-Stimulated Gene 6 (TSG-6) in Ischemic Brain Injury Caused by Middle Cerebral Artery …

C Di Santo, D La Russa, R Greco, A Persico… - International Journal of …, 2023 - mdpi.com
The identification of novel targets to modulate the immune response triggered by cerebral
ischemia is crucial to promote the development of effective stroke therapeutics. Since tumour …

[HTML][HTML] Cerebral protective effect of in situ and remote ischemic postconditioning on ischemic stroke rat via the TGFβ1-Smad2/3 signaling pathway

W Ma, J Yang, J Zhang, R He, Y Luo, C Li, F Zhao… - Brain Research, 2024 - Elsevier
Patients with acute ischemic stroke achieve inadequate benefit due to the short therapeutic
window for thrombolysis and the risk of ischemia/reperfusion (IR) injury. Ischemic …

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

Y Zhu, X Li, X Lei, L Tang, D Wen, B Zeng… - Neural Regeneration …, 2024 - journals.lww.com
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning
against stroke. Although numerous animal researches have shown that the neuroprotective …