Adoptive T cell therapy has been successfully used for treatment of viral and malignant
diseases. However, little is known about the fate and trafficking of transferred Ag-specific T …

Dendritic cell (DC)-based therapy has proved to be effective in patients with a variety of
malignancies. However, an optimal immunization protocol using DCs and the best means …

Lymphocyte motility is governed by a complex array of mechanisms, and highly dependent
on external microenvironmental cues. Tertiary lymphoid sites in particular have unique …

Abstract Helper (CD4+) T cells perform direct therapeutic functions and augment responses
of cells such as cytotoxic (CD8+) T cells against a wide variety of diseases and pathogens …

Pre‐eclampsia (PE) is the most severe pregnancy‐related disease, leading to high maternal
and fetal morbidity/mortality. Immunological imbalances associated with endothelial cell …

In this study, we report the adoptive transfer of highly tumor-reactive Melan-A-specific T cell
clones to patients with metastatic melanoma, and the follow-up of these injected cells. These …

Staphylococcus aureus and its toxins have been linked to disease progression and mortality
in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role …

Despite a dramatic increase in T-cell receptor (TCR) sequencing, few approaches
biologically parse the data in a fashion that both helps yield new information about immune …

The cytotoxic activity of T lymphocytes, natural killer and lymphokine-activated killer cells is
usually tested by radioactive assays, which detect the release of cytoplasmic contents after …

The adoptive transfer of in vitro-induced and expanded tumor-specific cytotoxic T
lymphocytes (CTL) presents a promising immunotherapeutic approach for the treatment of …