Publisher Summary This chapter provides an overview of cytometric cytokine secretion
assay used for the detection and isolation of cytokine-secreting T cells. The cytokine …

LVTKHGUGBGNBPL-UHFFFAOYSA-N 3-Amino-1, 4-dimethyl-5H-pyrido [4, 3-b] indole
Chemical compound N1C2= CC= CC= C2C2= C1C (C)= C (N) N= C2C …

Immune cell therapies have revolutionized our idea of a drug. Essentially they are a living
drug becoming increasingly used because of their specificity (antigen targeting), durability …

The invention provides fusion proteins comprising antigens of infectious disease agents and
cancer cells linked to multiple-trimer forms of TNF SuperFamily (TNFSF) ligands. The …

Interferon g (IFN-γ) is a regulatory cytokine with a broad spectrum of biologic activities and
considerable clinical importance. It is considered to be a master regulator of the immune …

Adoptive cell transfer techniques identify and isolate patient anti-tumor lymphocytes in vitro
followed by ex vivo expansion of these tumor specific T cells. Identification and isolation of …

The invention provides fusion proteins comprising antigens of infectious disease agents and
cancer cells linked to multiple-trimer forms of TNF SuperFamily (TNFSF) ligands. The …

The ability to examine the status of T cells offers insights to the immune response against a
disease and contributes to the formulation of effective therapies or vaccines. MHC tetramers …

DISCOVERY OF CD8 T CELL EPITOPES IN VIRAL DISEASES EMPLOYING CONDITIONAL
LIGANDS FOR MURINE MHC AND ASIAN HLA VARIANTS CHANG XI Page 1 DISCOVERY OF …

Malignant tumours are the second main cause of mortality worldwide, with haematological
malignancies representing 10%. Current treatment strategies, such as chemotherapy …