Flavonoids in cancer and apoptosis
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …
approaches to cancer treatment, they are often painful due to adverse side effects and are …
The fascinating effects of baicalein on cancer: a review
H Liu, Y Dong, Y Gao, Z Du, Y Wang, P Cheng… - International journal of …, 2016 - mdpi.com
Cancer is one of the leading causes of death worldwide and a major global health problem.
In recent decades, the rates of both mortality and morbidity of cancer have rapidly increased …
In recent decades, the rates of both mortality and morbidity of cancer have rapidly increased …
[HTML][HTML] An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways
Z Hu, Y Guan, W Hu, Z Xu, M Ishfaq - Iranian Journal of Basic …, 2022 - ncbi.nlm.nih.gov
The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …
Baicalein: A review of its anti-cancer effects and mechanisms in Hepatocellular Carcinoma
B Bie, J Sun, Y Guo, J Li, W Jiang, J Yang… - Biomedicine & …, 2017 - Elsevier
Abstract Baicalein (5, 6, 7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one) is a flavonoid
compound derived from the roots of Scutellaria baicalensis. It has historically been used in …
compound derived from the roots of Scutellaria baicalensis. It has historically been used in …
Autophagy: Mechanisms and therapeutic potential of flavonoids in cancer
X Pang, X Zhang, Y Jiang, Q Su, Q Li, Z Li - Biomolecules, 2021 - mdpi.com
Autophagy, which is a conserved biological process and essential mechanism in
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …
Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells
Poor prognoses remain the most challenging aspect of hepatocellular carcinoma (HCC)
therapy. Consequently, alternative therapeutics are essential to control HCC. This study …
therapy. Consequently, alternative therapeutics are essential to control HCC. This study …
Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cells
TW Kim - Acta Pharmacologica Sinica, 2022 - nature.com
Previous reports suggested that cinnamaldehyde (CA), the bioactive ingredient in
Cinnamomum cassia, can suppress tumor growth, migratory, and invasive abilities …
Cinnamomum cassia, can suppress tumor growth, migratory, and invasive abilities …
Phytochemicals as potent modulators of autophagy for cancer therapy
MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …
diseases, and accordingly universal research efforts have focused on exploring novel …
Phytochemicals as a complement to cancer chemotherapy: pharmacological modulation of the autophagy-apoptosis pathway
Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …
applications, and some display promising anticancer properties. Further evidence suggests …
Autophagy: a potential therapeutic target of polyphenols in hepatocellular carcinoma
Autophagy is a conserved biological phenomenon that maintains cellular homeostasis
through the clearing of damaged cellular components under cellular stress and offers the …
through the clearing of damaged cellular components under cellular stress and offers the …