A coordinated, multidisciplinary approach to care is essential for optimum management of
the primary manifestations and secondary complications of Duchenne muscular dystrophy …

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disorder. It is caused
by loss-of-function mutations in the dystrophin gene. Currently, there is no cure. A highly …

Muscular Dystrophy, convened a Working Group meeting on July 2014, in Bethesda, MD, to
explore clinical and research questions related to cardiac disease in patients with DMD. As …

Background: Loss of dystrophin protein causes Duchenne muscular dystrophy (DMD),
characterized by progressive degeneration of cardiac and skeletal muscles, and mortality in …

Muscular dystrophies are a group of diseases characterised by the primary wasting of
skeletal muscle, which compromises patient mobility and in the most severe cases originate …

Duchenne muscular dystrophy (DMD) is a rare X-linked recessive disease that is associated
with severe progressive muscle degeneration culminating in death due to cardiorespiratory …

Dystrophic cardiomyopathy is a significant feature of Duchenne muscular dystrophy (DMD).
Increased cardiomyocyte cytosolic calcium (Ca 2+) and interstitial fibrosis are major …

Introduction Duchenne muscular dystrophy (DMD) is the most common myopathy in
children, with a worldwide prevalence of approximately 0.5 cases per 10 000 male births. It …

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) offer
unprecedented opportunities to study inherited heart conditions in vitro, but are …

X-linked dilated cardiomyopathy (XLDCM) is a distinct phenotype of dystrophinopathy
characterized by preferential cardiac involvement without any overt skeletal myopathy …