Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …

This study aimed to develop microspheres using water-soluble carriers and surfactants to
improve the solubility, dissolution, and oral bioavailability of rivaroxaban (RXB). RXB-loaded …

In the current study, lipid-polymer hybrid nanoparticles (LPHNPs) fabricated with lipoid-90H
and chitosan, sunitinib malate (SM), an anticancer drug was loaded using lecithin as a …

Baricitinib (BTB) is an orally administered Janus kinase inhibitor, therapeutically used for the
treatment of rheumatoid arthritis. Recently it has also been approved for the treatment of …

Olaparib (OLP) is an orally active poly (ADP-ribose) polymerase enzyme inhibitor, approved
for treatment for the metastatic stage of prostate, pancreatic, breast and ovarian cancer. Due …

In the present study, ribociclib-loaded nanosponges (RCNs) composed of ethylcellulose and
polyvinyl alcohol were developed using an emulsion-solvent evaporation method …

Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

Inflammatory regulation induced by macrophage polarization is essential for cardiac repair
after myocardial infarction (MI). Berberin (BBR) is an isoquinoline tetrasystemic alkaloid …

Rivaroxaban (RVX), an oral direct factor Xa inhibitor, is being explored as an alternative to
traditional anticoagulans. However, RVX still faces pharmacokinetic limitations and adverse …

BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often
have an incomplete or erratic absorption profile. This study aimed to predict the effects of β …