Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Immune cells in the epithelial immune microenvironment of psoriasis: emerging therapeutic targets

L Li, J Lu, J Liu, J Wu, X Zhang, Y Meng, X Wu… - Frontiers in …, 2024 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …

[HTML][HTML] Apremilast loaded lyotropic liquid crystalline nanoparticles embedded hydrogel for improved permeation and skin retention: An effective approach for …

VK Rapalli, Y Tomar, S Sharma, A Roy… - Biomedicine & …, 2023 - Elsevier
The present work aimed to prepare and evaluate Apremilast loaded lyotropic liquid
crystalline nanoparticles (LCNPs) formulation for skin delivery to enhance the efficacy with …

Evolving trends in nanofibers for topical delivery of therapeutics in skin disorders

Y Tomar, N Pandit, S Priya, G Singhvi - ACS omega, 2023 - ACS Publications
Nanotechnology has yielded nanostructure-based drug delivery approaches, among which
nanofibers have been explored and researched for the potential topical delivery of …

Enhanced skin drug delivery using dissolving microneedles: a potential approach for the management of skin disorders

S Priya, Y Tomar, VM Desai… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction For decades, finding effective long-term or disease-modifying treatments for skin
disorders has been a major focus of scientists. The conventional drug delivery systems …

Navigating the landscape of psoriasis therapy: novel targeted pathways and emerging trends

S Innani, Y Tomar, V Rana… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Psoriasis is a chronic, inflammatory, non-communicable skin disorder that
affects a patient's social and emotional well-being. It is characterized by hyperproliferation of …

Ruxolitinib attenuates microglial inflammatory response by inhibiting NF-κB/MAPK signaling pathway

J Min, H Zheng, H Xia, X Tian, M Liang, J Zhang… - European Journal of …, 2024 - Elsevier
Neuroinflammation is involved in the physiological and pathological processes of numerous
neurological diseases, and its inhibition seems to be a promising therapeutic direction for …

Curcumin loaded liquid crystalline nanoparticles for enhanced topical application: Design, characterization, ex vivo and dermatokinetic evaluation

Y Tomar, S Maheshwari, S Gorantla… - Journal of Drug Delivery …, 2024 - Elsevier
Despite its effectiveness, topical delivery of curcumin (CUR) is restrained by its limited
aqueous solubility and inadequate skin retention and permeation. Through this research …

Bibliometric analysis and description of research trends on T cells in psoriasis over the past two decades (2003–2022)

J Li, J Zhang, C Guo, P Lin, Q Shen, H Lin, Y Zhang - Heliyon, 2023 - cell.com
Background It is now understood that T cells play a key role in the occurrence and
development of psoriasis. Herein, a bibliometric analysis was conducted to summarize the …

[HTML][HTML] Advances in Electrospun Nanofiber Membranes for Dermatological Applications: A Review

Y Han, H Wei, Q Ding, C Ding, S Zhang - Molecules, 2024 - mdpi.com
In recent years, a wide variety of high-performance and versatile nanofiber membranes have
been successfully created using different electrospinning methods. As vehicles for …