Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?
K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …
research following several theoretical and clinical lines, all existing treatments for the …
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis
A Kontush, MJ Chapman - Pharmacological reviews, 2006 - ASPET
High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
Crosstalk between long noncoding RNAs and microRNAs in health and disease
AS Bayoumi, A Sayed, Z Broskova, JP Teoh… - International journal of …, 2016 - mdpi.com
Protein-coding genes account for only a small part of the human genome; in fact, the vast
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …
majority of transcripts are comprised of non-coding RNAs (ncRNAs) including long ncRNAs …
Mouse models for atherosclerosis and pharmaceutical modifiers
S Zadelaar, R Kleemann, L Verschuren… - … , and vascular biology, 2007 - Am Heart Assoc
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that
work synergistically to promote lesion development. The ability to develop preventive and …
work synergistically to promote lesion development. The ability to develop preventive and …
Effects of diet on brain plasticity in animal and human studies: mind the gap
Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …
Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB–driven inflammation and atherosclerosis
K Li, D Ching, FS Luk, RL Raffai - Circulation research, 2015 - Am Heart Assoc
Rationale: Apolipoprotein E (apoE) exerts anti-inflammatory properties that protect against
atherosclerosis and other inflammatory diseases. However, mechanisms by which apoE …
atherosclerosis and other inflammatory diseases. However, mechanisms by which apoE …
ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia‐driven hematopoiesis & inflammation via extracellular …
While apolipoprotein E (apoE) expression by myeloid cells is recognized to control
inflammation, whether such benefits can be communicated via extracellular vesicles is not …
inflammation, whether such benefits can be communicated via extracellular vesicles is not …
Large animal models of cardiovascular disease
HG Tsang, NA Rashdan, CBA Whitelaw… - Cell biochemistry …, 2016 - Wiley Online Library
The human cardiovascular system is a complex arrangement of specialized structures with
distinct functions. The molecular landscape, including the genome, transcriptome and …
distinct functions. The molecular landscape, including the genome, transcriptome and …
Roles of coagulation proteases and PARs (protease-activated receptors) in mouse models of inflammatory diseases
Activation of the blood coagulation cascade leads to fibrin deposition and platelet activation
that are required for hemostasis. However, aberrant activation of coagulation can lead to …
that are required for hemostasis. However, aberrant activation of coagulation can lead to …
[PDF][PDF] Functional benefits of citrus fruits in the management of diabetes
OI Aruoma, B Landes, D Ramful-Baboolall… - Preventive …, 2012 - blog.univ-reunion.fr
Citrus fruits are important fruit tree crops in the world and are among the most consumed
fruits after mangoes, tomatoes and bananas. Citrus fruits (Fig. 1 and Table 1) not only …
fruits after mangoes, tomatoes and bananas. Citrus fruits (Fig. 1 and Table 1) not only …