Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …

Purpose Doxorubicin (DOX) is a highly active antineoplastic agent; however, its clinical use
is limited due to associated cardiotoxicity. This study was performed to evaluate the …

Background As an anthracycline antibiotic, doxorubicin (DOX) is one of the most potent and
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …

Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

Aims Cognitive decline is one of the most challenging issues for cancer survivors
undergoing doxorubicin (DOX) based chemotherapy. Oxidative stress and inflammation …

Doxorubicin (DOX) is a potent and widely used anthracycline antibiotic for the treatment of
several malignancies. Unfortunately, the clinical utility of DOX is often restricted due to the …

Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …

Chemotherapy and radiotherapy are mainstay treatments for cancer patients. However, their
clinical outcomes are highly limited by the resistance of malignant tumors to these therapies …