Microglia are so versatile that they not only provide immune surveillance for central nervous
system, but participate in neural circuitry development, brain blood vessels formation, blood …

Aberrant activation of the Janus kinase (JAK) and signal transducer and activator of
transcription (STAT) pathway is common in systemic lupus erythematosus (SLE), conferring …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a recent
worldwide coronavirus disease-2019 (COVID-19) pandemic. SARS-CoV-2 primarily causes …

Background Cellular identity is determined partly by cell type-specific epigenomic profiles
that regulate gene expression. In neuroscience, there is a pressing need to isolate and …

Systemic lupus erythematosus (SLE) is an inflammatory disorder related to immunity
dysfunction. The Th1 cell family including Th1 cells, transcription factor T-bet, and related …

Rheumatoid factor (RF), an established diagnostic biomarker for rheumatoid arthritis (RA), is
associated with cardiovascular diseases, but its impact on clinical outcomes of ischemic …

Rheumatoid arthritis (RA) can independently increase the risk of stroke, affecting both young
and adult RA patients. Recent attention has been drawn to the association between stroke …

Stroke is a clinical syndrome characterized by an acute, focal neurological deficit, primarily
caused by the occlusion or rupture of cerebral blood vessels. In stroke, neuroinflammation …

Background Sleep loss is a common public health problem that causes hyperalgesia,
especially that after surgery, which reduces the quality of life seriously. Methods The 48-h …

Background Neuropsychiatric lupus (NPSLE) describes the cognitive, memory, and affective
emotional burdens faced by many lupus patients. While NPSLE's pathogenesis has not …