Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Taxol is a potent drug used in various cancer treatments. Its complex structure has prompted
extensive research into its biosynthesis. However, certain critical steps, such as the …
extensive research into its biosynthesis. However, certain critical steps, such as the …
Exploring the evolvability of plant specialized metabolism: uniqueness out of uniformity and uniqueness behind uniformity
E Ono, J Murata - Plant and Cell Physiology, 2023 - academic.oup.com
The huge structural diversity exhibited by plant specialized metabolites has primarily been
considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly …
considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly …
Plant terpenoid biosynthetic network and its multiple layers of regulation
Terpenoids constitute one of the largest and most chemically diverse classes of primary and
secondary metabolites in nature with an exceptional breadth of functional roles in plants …
secondary metabolites in nature with an exceptional breadth of functional roles in plants …
[HTML][HTML] Reconstitution of early paclitaxel biosynthetic network
JCT Liu, R De La Peña, C Tocol, ES Sattely - Nature Communications, 2024 - nature.com
Paclitaxel is an anticancer therapeutic produced by the yew tree. Over the last two decades,
a significant bottleneck in the reconstitution of early paclitaxel biosynthesis has been the …
a significant bottleneck in the reconstitution of early paclitaxel biosynthesis has been the …
[HTML][HTML] Microbial fortification of pharmacological metabolites in medicinal plants
X Wu, Y Yang, H Zhang - Computational and Structural Biotechnology …, 2023 - Elsevier
Medicinal plants are rich in secondary metabolites with beneficial pharmacological effects.
The production of plant secondary metabolites is subjected to the influences by …
The production of plant secondary metabolites is subjected to the influences by …
[HTML][HTML] Comparative transcriptomics of two Salvia subg. Perovskia species contribute towards molecular background of abietane-type diterpenoid biosynthesis
Tanshinones, are a group of diterpenoid red pigments present in Danshen–an important
herbal drug of Traditional Chinese Medicine which is a dried root of Salvia miltiorrhiza …
herbal drug of Traditional Chinese Medicine which is a dried root of Salvia miltiorrhiza …
Complete pathway elucidation and heterologous reconstitution of (+)‐nootkatone biosynthesis from Alpinia oxyphylla
X Deng, Z Ye, J Duan, F Chen, Y Zhi, M Huang… - New …, 2024 - Wiley Online Library
Nootkatone is a natural sesquiterpene ketone widely used in food, cosmetics,
pharmaceuticals, and agriculture. It is also regarded as one of the most valuable terpenes …
pharmaceuticals, and agriculture. It is also regarded as one of the most valuable terpenes …
[HTML][HTML] Stressing the importance of plant specialized metabolites: omics-based approaches for discovering specialized metabolism in plant stress responses
M Wu, TR Northen, Y Ding - Frontiers in Plant Science, 2023 - frontiersin.org
Plants produce a diverse range of specialized metabolites that play pivotal roles in
mediating environmental interactions and stress adaptation. These unique chemical …
mediating environmental interactions and stress adaptation. These unique chemical …
[HTML][HTML] Stressing the importance of plant specialized metabolites: omics-based approaches for discovering specialized metabolism in plant stress responses
M Wu, TR Northen, Y Ding - Frontiers in Plant Science, 2023 - frontiersin.org
Plants produce a diverse range of specialized metabolites that play pivotal roles in
mediating environmental interactions and stress adaptation. These unique chemical …
mediating environmental interactions and stress adaptation. These unique chemical …
[HTML][HTML] Genomic analysis based on chromosome-level genome assembly reveals Myrtaceae evolution and terpene biosynthesis of rose myrtle
L Yang, J Jin, S Lyu, F Zhang, P Cao, Q Qin, G Zhang… - BMC genomics, 2024 - Springer
Abstract Background Rose myrtle (Rhodomyrtus tomentosa (Ait.) Hassk), is an evergreen
shrub species belonging to the family Myrtaceae, which is enriched with bioactive volatiles …
shrub species belonging to the family Myrtaceae, which is enriched with bioactive volatiles …