Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
A critical evaluation of risk to reward ratio of quercetin supplementation for COVID‐19 and associated comorbid conditions
A Pawar, M Russo, I Rani, K Goswami… - Phytotherapy …, 2022 - Wiley Online Library
The interim results of the large, multinational trials on coronavirus disease 2019 (COVID‐19)
using a combination of antiviral drugs appear to have little to no effect on the 28‐day …
using a combination of antiviral drugs appear to have little to no effect on the 28‐day …
Predicting response to benralizumab in chronic obstructive pulmonary disease: analyses of GALATHEA and TERRANOVA studies
Background Benralizumab did not significantly reduce exacerbations compared with
placebo in the phase 3 GALATHEA and TERRANOVA trials of benralizumab for patients …
placebo in the phase 3 GALATHEA and TERRANOVA trials of benralizumab for patients …
[HTML][HTML] Mortality in obstructive sleep apnea syndrome (OSAS) and overlap syndrome (OS): The role of nocturnal hypoxemia and CPAP compliance
P Tondo, G Scioscia, R Sabato, R Leccisotti… - Sleep Medicine, 2023 - Elsevier
Background Obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary
disease (COPD) are two chronic diseases that afflict many individuals worldwide with …
disease (COPD) are two chronic diseases that afflict many individuals worldwide with …
Five-year progression of emphysema and air trapping at CT in smokers with and those without chronic obstructive pulmonary disease: results from the COPDGene …
E Pompe, M Strand, EM van Rikxoort, EA Hoffman… - Radiology, 2020 - pubs.rsna.org
Background CT is used to quantify abnormal changes in the lung parenchyma of smokers
that might overlap chronic obstructive pulmonary disease (COPD), but studies on the …
that might overlap chronic obstructive pulmonary disease (COPD), but studies on the …
High eosinophil counts predict decline in FEV1: results from the CanCOLD study
WC Tan, J Bourbeau, G Nadeau… - European …, 2021 - Eur Respiratory Soc
Introduction The aim of this study was to examine the association between blood eosinophil
levels and the decline in lung function in individuals aged> 40 years from the general …
levels and the decline in lung function in individuals aged> 40 years from the general …
Safety of eosinophil-depleting therapy for severe, eosinophilic asthma: focus on benralizumab
DJ Jackson, S Korn, SK Mathur, P Barker, VG Meka… - Drug safety, 2020 - Springer
Eosinophils play a pivotal role in the inflammatory pathology of asthma and have been the
target of new biologic treatments for patients with eosinophilic asthma. Given the central role …
target of new biologic treatments for patients with eosinophilic asthma. Given the central role …
Inhaled corticosteroids and risk of pneumonia in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials
M Yang, Y Du, H Chen, D Jiang, Z Xu - International immunopharmacology, 2019 - Elsevier
Objective Inhaled corticosteroids (ICS) are generally used to treat patients with chronic
obstructive pulmonary disease (COPD) who suffer from repeated exacerbations. Recently, it …
obstructive pulmonary disease (COPD) who suffer from repeated exacerbations. Recently, it …
Bacteria and sputum inflammatory cell counts; a COPD cohort analysis
Background There is evidence that bacterial colonisation in chronic obstructive pulmonary
disease (COPD) is associated with increased neutrophilic airway inflammation. This study …
disease (COPD) is associated with increased neutrophilic airway inflammation. This study …
Effect of pulmonary hypertension on exercise tolerance in patients with COPD: a prognostic systematic review and meta-analysis
R Torres-Castro, E Gimeno-Santos… - European …, 2021 - Eur Respiratory Soc
Background Pulmonary hypertension (PH) is a frequent complication in patients with COPD.
Objective To determine if, in patients with COPD, the presence of PH decreases exercise …
Objective To determine if, in patients with COPD, the presence of PH decreases exercise …