Health care-associated infections–an overview

M Haque, M Sartelli, J McKimm… - Infection and drug …, 2018 - Taylor & Francis
Health care-associated infections (HCAIs) are infections that occur while receiving health
care, developed in a hospital or other health care facility that first appear 48 hours or more …

Facing up to the global challenges of ageing

L Partridge, J Deelen, PE Slagboom - Nature, 2018 - nature.com
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

Polypharmacy in older adults hospitalized for heart failure

O Unlu, EB Levitan, E Reshetnyak… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: Despite potential harm that can result from polypharmacy, real-world data on
polypharmacy in the setting of heart failure (HF) are limited. We sought to address this …

Machine learning on adverse drug reactions for pharmacovigilance

CY Lee, YPP Chen - Drug discovery today, 2019 - Elsevier
An adverse drug reaction (ADR) is an unintended response to a drug that is noxious and the
reaction has a causal relationship to the drug 1, 2, 3, 4, 5. It is disturbing that∼ 3.6% of all …

REview of potentially inappropriate MEDIcation pr [e] scribing in Seniors (REMEDI [e] S): French implicit and explicit criteria

B Roux, J Berthou-Contreras, JB Beuscart… - European Journal of …, 2021 - Springer
Purpose To establish a consensus on both explicit and implicit criteria in order to identify
potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or …

Prediction of hospitalization due to adverse drug reactions in elderly community-dwelling patients (the PADR-EC score)

N Parameswaran Nair, L Chalmers, M Connolly… - PLoS …, 2016 - journals.plos.org
Background Adverse drug reactions (ADRs) are the major cause of medication-related
hospital admissions in older patients living in the community. This study aimed to develop …

Systematic review of predictive risk models for adverse drug events in hospitalized patients

N Falconer, M Barras, N Cottrell - British journal of clinical …, 2018 - Wiley Online Library
Aim An emerging approach to reducing hospital adverse drug events is the use of predictive
risk scores. The aim of this systematic review was to critically appraise models developed for …

Development of a standardized chart review method to identify drug‐related hospital admissions in older people

S Thevelin, A Spinewine, JB Beuscart… - British journal of …, 2018 - Wiley Online Library
Aims We aimed to develop a standardized chart review method to identify drug‐related
hospital admissions (DRA) in older people caused by non‐preventable adverse drug …

[HTML][HTML] Concurrent use of polypharmacy and potentially inappropriate medications with antidepressants in older adults: a nationwide descriptive study in Denmark …

K Ishtiak-Ahmed, O Köhler-Forsberg… - General Hospital …, 2023 - Elsevier
Objective Concurrent polypharmacy and potentially-inappropriate-medication (PIMs) use
with antidepressants in older adults is understudied. We investigated the prevalence and …

Associations between polypharmacy, self-rated health, and depression in African American older adults; mediators and moderators

M Bazargan, J Smith, M Saqib, H Helmi… - International journal of …, 2019 - mdpi.com
Background. Despite the prevalence of multimorbidity among African American (AA) older
adults, little information exists on correlates of polypharmacy (using 5+ medications) in AA …