Sepsis remains a major therapeutic challenge and is associated with a high rate of morbidity
and mortality. It is a dynamic condition in which multiple parameters change over time …

Fever represents an elevation of body temperature, that exerts a protective effect against
pathogens. Innate immune cells and neurons are implicated in the regulation of body …

Increasing evidence indicates that patients or experimental animals exposure to endotoxin
(lipopolysaccharides, LPS) exert deleterious cardiac functions that greatly contribute to …

Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus,
causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%. While …

To screen potential pivotal targets in sepsis through peripheral blood. Septic patients (n= 23)
and healthy volunteers (n= 10) were enrolled according to SEPSIS 3.0. Peripheral blood …

Background and Purpose Lipopolysaccharides (LPS), an outer membrane component of
Gram‐negative bacteria, triggers myocardial anomalies in sepsis. Recent findings indicated …

Background & Objectives: In old people, both innate and adaptive immune responses are
impaired, thus leading to a condition of systemic inflamm-ageing, even including the …

The progress of sepsis is increasingly recognized by the transition from early
hyperinflammation to long term immunosuppression, which is characterized in innate …

Background: Neutrophils to lymphocytes and platelets (N/LP) ratio has been confirmed as
an indirect marker of inflammation. In this study, we aimed to further evaluate the prognostic …

Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a lifesaving
maneuver for the management of lethal torso hemorrhage. However, its prolonged use …