Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Since its publication in 1950, the Biology of Human Starvation, which describes the classic
longitudinal Minnesota Experiment of semistarvation and refeeding in healthy young men …

Caloric restriction that promotes weight loss is an effective strategy for treating non-alcoholic
fatty liver disease and improving insulin sensitivity in people with type 2 diabetes. Despite its …

Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Background The popularity of applying intermittent fasting (IF) has increased as more and
more people are trying to avoid or alleviate obesity and metabolic disease. This study aimed …

Current healthcare is weight‐centric, equating weight and health. This approach to
healthcare has negative consequences on patient well‐being. The aim of this article is to …

Preserving skeletal muscle function is essential to maintain life quality at high age. Calorie
restriction (CR) potently extends health and lifespan, but is largely unachievable in humans …

OBJECTIVE SGTL2 inhibitors increase urinary glucose excretion and have beneficial effects
on cardiovascular and renal outcomes. The underlying mechanism may involve caloric …

Weight regain after successful weight loss resulting from lifestyle interventions is a major
challenge in the management of overweight and obesity. Knowledge of the causal …

On average, aging is associated with unfavorable changes in cellular metabolism, which are
the processes involved in the storage and expenditure of energy. However, metabolic …