Ocular drug delivery is one of the most challenging endeavors among the various available
drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic …

Topical drug delivery to the posterior segment of the eye is a very complex challenge.
However, topical delivery is highly desired, to achieve an easy-to-use treatment option for …

Background Neurological and ophthalmological neurodegenerative diseases in large part
share underlying biology and pathophysiology. Despite extensive preclinical research on …

Glaucoma, an age-related neurodegenerative disease, is characterized by the death of
retinal ganglion cells (RGCs) and the corresponding loss of visual fields. This disease is the …

Prostaglandin (PG) receptors represent important druggable targets due to the many diverse
actions of PGs in the body. From an ocular perspective, the discovery, development, and …

The peripheral nervous system (PNS) of mammals and nervous systems of lower organisms
possess significant regenerative potential. In contrast, although neural plasticity can provide …

Recently, various novel drug delivery systems have been developed to overcome ocular
barriers in order to improve drug efficacy. We have previously reported that montmorillonite …

A multitude of pharmacological compounds have been shown to lower and control
intraocular pressure (IOP) in numerous species of animals and human subjects after topical …

More than 76 million people worldwide are afflicted with the neurodegenerative eye
diseases described and grouped together as glaucoma. A common feature amongst the …

Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and
microbes pervade our environment. Inflammatory and allergic mediators released by …