Immune system, friend or foe of oncolytic virotherapy?

AC Filley, M Dey - Frontiers in oncology, 2017 - frontiersin.org
Oncolytic viruses (OVs) are an emerging class of targeted anticancer therapies designed to
selectively infect, replicate in, and lyse malignant cells without causing harm to normal …

Omicron BA.2 breakthrough infection elicits CD8+ T cell responses recognizing the spike of later Omicron subvariants

SH Kim, J Kim, S Jung, JY Noh, J Kim, H Park… - Science …, 2024 - science.org
Here, we examine peripheral blood memory T cell responses against the SARS-CoV-2 BA.
4/BA. 5 variant spike among vaccinated individuals with or without Omicron breakthrough …

Immune defence, parasite evasion strategies and their relevance for 'macroscopic phenomena'such as virulence

P Schmid-Hempel - … Transactions of the Royal Society B …, 2009 - royalsocietypublishing.org
The discussion of host–parasite interactions, and of parasite virulence more specifically, has
so far, with a few exceptions, not focused much attention on the accumulating evidence that …

Flying under the radar: the immunobiology of hepatitis C

LB Dustin, CM Rice - Annu. Rev. Immunol., 2007 - annualreviews.org
The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent
infection in more than two-thirds of those who contract it. Its success is related to its abilities …

Human pathogenic hantaviruses and prevention of infection

DH Krüger, G Schönrich, B Klempa - Human vaccines, 2011 - Taylor & Francis
Hantaviruses are emerging viruses which are hosted by small mammals. When transmitted
to humans, they can cause two clinical syndromes, hemorrhagic fever with renal syndrome …

Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells

S Nguyen, C Deleage, S Darko, A Ransier… - Science translational …, 2019 - science.org
The functional properties of circulating CD8+ T cells have been associated with immune
control of HIV. However, viral replication occurs predominantly in secondary lymphoid …

Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response

D Theil, T Derfuss, I Paripovic, S Herberger… - The American journal of …, 2003 - Elsevier
The majority of trigeminal ganglia (TGs) are latently infected with α-herpesviruses [herpes
simplex virus type-1 (HSV-1) and varicella-zoster virus (VZV)]. Whereas HSV-1 periodically …

[HTML][HTML] Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice

H Jacomy, G Fragoso, G Almazan, WE Mushynski… - Virology, 2006 - Elsevier
The notion that an infectious respiratory pathogen can damage the central nervous system
(CNS) and lead to neurological disease was tested using a human respiratory coronavirus …

Hepatitis B virus infection: overview

H Li, L Yan, Y Shi, D Lv, J Shang, L Bai… - Hepatitis B Virus Infection …, 2020 - Springer
Hepatitis B virus (HBV) is a DNA virus, belonging to the Hepadnaviridae family. It is a
partially double-stranded DNA virus with a small viral genome (3.2 kb). Chronic HBV …

[PDF][PDF] Hepatitis E virus (HEV)‐specific T‐cell responses are associated with control of HEV infection

PV Suneetha, S Pischke, V Schlaphoff… - …, 2012 - Wiley Online Library
Hepatitis E virus (HEV) infection is usually self‐limited but may lead to acute hepatitis and
rarely to fulminant hepatic failure. Persistent HEV infections have recently been described in …