Immune system, friend or foe of oncolytic virotherapy?
Oncolytic viruses (OVs) are an emerging class of targeted anticancer therapies designed to
selectively infect, replicate in, and lyse malignant cells without causing harm to normal …
selectively infect, replicate in, and lyse malignant cells without causing harm to normal …
Omicron BA.2 breakthrough infection elicits CD8+ T cell responses recognizing the spike of later Omicron subvariants
SH Kim, J Kim, S Jung, JY Noh, J Kim, H Park… - Science …, 2024 - science.org
Here, we examine peripheral blood memory T cell responses against the SARS-CoV-2 BA.
4/BA. 5 variant spike among vaccinated individuals with or without Omicron breakthrough …
4/BA. 5 variant spike among vaccinated individuals with or without Omicron breakthrough …
Immune defence, parasite evasion strategies and their relevance for 'macroscopic phenomena'such as virulence
P Schmid-Hempel - … Transactions of the Royal Society B …, 2009 - royalsocietypublishing.org
The discussion of host–parasite interactions, and of parasite virulence more specifically, has
so far, with a few exceptions, not focused much attention on the accumulating evidence that …
so far, with a few exceptions, not focused much attention on the accumulating evidence that …
Flying under the radar: the immunobiology of hepatitis C
LB Dustin, CM Rice - Annu. Rev. Immunol., 2007 - annualreviews.org
The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
Human pathogenic hantaviruses and prevention of infection
DH Krüger, G Schönrich, B Klempa - Human vaccines, 2011 - Taylor & Francis
Hantaviruses are emerging viruses which are hosted by small mammals. When transmitted
to humans, they can cause two clinical syndromes, hemorrhagic fever with renal syndrome …
to humans, they can cause two clinical syndromes, hemorrhagic fever with renal syndrome …
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells
S Nguyen, C Deleage, S Darko, A Ransier… - Science translational …, 2019 - science.org
The functional properties of circulating CD8+ T cells have been associated with immune
control of HIV. However, viral replication occurs predominantly in secondary lymphoid …
control of HIV. However, viral replication occurs predominantly in secondary lymphoid …
Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response
D Theil, T Derfuss, I Paripovic, S Herberger… - The American journal of …, 2003 - Elsevier
The majority of trigeminal ganglia (TGs) are latently infected with α-herpesviruses [herpes
simplex virus type-1 (HSV-1) and varicella-zoster virus (VZV)]. Whereas HSV-1 periodically …
simplex virus type-1 (HSV-1) and varicella-zoster virus (VZV)]. Whereas HSV-1 periodically …
[HTML][HTML] Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice
H Jacomy, G Fragoso, G Almazan, WE Mushynski… - Virology, 2006 - Elsevier
The notion that an infectious respiratory pathogen can damage the central nervous system
(CNS) and lead to neurological disease was tested using a human respiratory coronavirus …
(CNS) and lead to neurological disease was tested using a human respiratory coronavirus …
Hepatitis B virus infection: overview
H Li, L Yan, Y Shi, D Lv, J Shang, L Bai… - Hepatitis B Virus Infection …, 2020 - Springer
Hepatitis B virus (HBV) is a DNA virus, belonging to the Hepadnaviridae family. It is a
partially double-stranded DNA virus with a small viral genome (3.2 kb). Chronic HBV …
partially double-stranded DNA virus with a small viral genome (3.2 kb). Chronic HBV …
[PDF][PDF] Hepatitis E virus (HEV)‐specific T‐cell responses are associated with control of HEV infection
PV Suneetha, S Pischke, V Schlaphoff… - …, 2012 - Wiley Online Library
Hepatitis E virus (HEV) infection is usually self‐limited but may lead to acute hepatitis and
rarely to fulminant hepatic failure. Persistent HEV infections have recently been described in …
rarely to fulminant hepatic failure. Persistent HEV infections have recently been described in …