The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …

A series of sixteen β-carbolines, bearing chalcone moiety at C-1 position, were prepared
from easily accessible 1-acetyl-β-carboline and various aldehydes under basic conditions …

Kesari Lakshmi Manasa,* a Sanam Swetha Yadav, a Danaboina Srikanth, a Narayana
Nagesh,* b and Mallika Alvala* a aDepartment of Medicinal Chemistry, National Institute of …

Developing and excavating new agrochemicals with highly active and safe is an important
tactic for protecting crop health and food safety. In this paper, to discover the new bactericide …

Fluoroquinolones are broad-spectrum antibiotics that target gyrase and topoisomerase IV,
involved in DNA compaction and segregation. We synthesized 28 novel norfloxacin …

To explore the effect of the introduction of the amino and substituted amino groups on the
antitumor activity of harmine, twenty-five novel 6-amino substituted harmine derivatives (3a …

A series of novel N 9-heterobivalent β-carbolines has been synthesized. All the novel
compounds were tested for their anticancer activity against six tumour cell lines in vitro …

Harmine, one of the natural β-carboline alkaloids extracted from Peganum harmala L.,
exhibits broad spectrum but limited insecticidal ability against many pests. So there is an …

A facile and practical [Cp* RhCl2] 2-catalyzed three-component reaction between indolyl
aldehydes, amines and alkynes involving C–H activation and cyclization has been …

Cell proliferation assays are performed by four decades to test the anti‐proliferative activity
of natural products and synthetic compounds in cell cultures. In cancer research, they are …