Chemotherapy side-effects: not all DNA damage is equal

WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

Childhood cancer: survival, treatment modalities, late effects and improvements over time

F Erdmann, LE Frederiksen, A Bonaventure… - Cancer …, 2021 - Elsevier
Since the 1960s, paediatric oncologists have gradually become better organised in large
study groups and participation in clinical trials is today considered as the standard of care …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T López-Fernández, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE)

N Bhakta, Q Liu, KK Ness, M Baassiri, H Eissa, F Yeo… - The Lancet, 2017 - thelancet.com
Background Survivors of childhood cancer develop early and severe chronic health
conditions (CHCs). A quantitative landscape of morbidity of survivors, however, has not …

Clinical ascertainment of health outcomes among adults treated for childhood cancer

MM Hudson, KK Ness, JG Gurney, DA Mulrooney… - Jama, 2013 - jamanetwork.com
Importance Adult survivors of childhood cancer are known to be at risk for treatment-related
adverse health outcomes. A large population of survivors has not been evaluated using a …

Survivors of childhood and adolescent cancer: life-long risks and responsibilities

LL Robison, MM Hudson - Nature Reviews Cancer, 2014 - nature.com
Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

Temporal patterns in the risk of chronic health conditions in survivors of childhood cancer diagnosed 1970–99: a report from the Childhood Cancer Survivor Study …

TM Gibson, S Mostoufi-Moab, KL Stratton… - The Lancet …, 2018 - thelancet.com
Background Treatments for childhood cancer have evolved over the past 50 years, with the
goal of maximising the proportion of patients who achieve long-term survival, while …

[HTML][HTML] Modifiable risk factors and major cardiac events among adult survivors of childhood cancer

GT Armstrong, KC Oeffinger, Y Chen… - Journal of clinical …, 2013 - ncbi.nlm.nih.gov
Modifiable Risk Factors and Major Cardiac Events Among Adult Survivors of Childhood
Cancer - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

[HTML][HTML] Aging and risk of severe, disabling, life-threatening, and fatal events in the childhood cancer survivor study

GT Armstrong, T Kawashima, W Leisenring… - Journal of clinical …, 2014 - ncbi.nlm.nih.gov
Purpose The first generation of childhood cancer survivors is now aging into their fourth and
fifth decades of life, yet health risks across the aging spectrum are not well established …

[HTML][HTML] Doxorubicin induced heart failure: Phenotype and molecular mechanisms

MA Mitry, JG Edwards - IJC heart & vasculature, 2016 - Elsevier
Long term survival of childhood cancers is now more than 70%. Anthracyclines, including
doxorubicin, are some of the most efficacious anticancer drugs available. However, its use …