Tumour initiation and progression requires the metabolic reprogramming of cancer cells.
Cancer cells autonomously alter their flux through various metabolic pathways in order to …

Hypervalent aryliodoumiums are intensively investigated as arylating agents. They are
excellent surrogates to aryl halides, and moreover they exhibit better reactivity, which allows …

Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …

Oncogene‐induced hyper‐proliferation in cancer cells is accompanied by the onset of
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …

Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance
between reactive oxygen and nitrogen species in the body and its ability to neutralize them …

Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

Severe durable changes may occur to the DNA structure caused by exogenous and
endogenous risk factors initiating the process of carcinogenesis. By evidence, a large …

The actin cytoskeleton of eukaryotic cells is a dynamic, fibrous network that is regulated by
the concerted action of actin-binding proteins (ABPs). In particular, rapid polarization of cells …