[PDF][PDF] Mechanism of gallium-67 accumulation in tumors

MF Tsan, U Scheffel - Journal of nuclear medicine, 1986 - Soc Nuclear Med
Min-Fu Tsan and Ursula Scheffel shown that 67Gain normal plasma isalmost exclusively
bound to transferrin. Like Fe3@, 67Ga binds to the two specific metal binding sites of human …

Gallium and other main group metal compounds as antitumor agents

MA Jakupec, BK Keppler - Metal ions in biological systems, 2004 - api.taylorfrancis.com
Gallium salts have been explored for their applicability as antineoplastic drugs for more than
two decades, but clinical experience has revealed unfavorable pharmacokinetic and …

Association of intratumoral pharmacokinetics of fluorouracil with clinical response

CA Presant, W Wolf, V Waluch, C Wiseman, P Kennedy… - The Lancet, 1994 - Elsevier
In-vivo fluorine-19 nuclear magnetic resonance spectroscopy (NMRS) allows non-invasive,
real-time, chemical identification of specific fluorinated compounds inside human tumours …

Current role of gallium scanning in the management of lymphoma

AF McLaughlin, MA Magee, R Greenough… - European journal of …, 1990 - Springer
Gallium 67 scanning in the malignant lympho mas has been done, with variable success, for
over 20 years. After initial enthusiasm, the technique fell into disrepute and it was not until …

[PDF][PDF] Uptake of gallium-67 in transfected cells and tumors absent or enriched in the transferrin receptor

CA Luttropp, JA Jackson, BJ Jones… - Journal of Nuclear …, 1998 - Soc Nuclear Med
(1). Subsequently, 67Gahas been shown to localize in a variety of tumors (2, 3). In nuclear
medicine, the utility of 67Ga as a tumor-imaging agent is variable. Many types of tumors …

The role of gallium-67 imaging in the detection of foci in recent cases of fever of unknown origin

K Suga, K Nakagi, T Kuramitsu, K Itou… - Annals of Nuclear …, 1991 - Springer
We have assembled data from patients with fever of unknown origin who underwent gallium
scintigraphy during the past 5 years in order to obtain a more current sampling of patients …

Pathophysiology and mechanisms of radiopharmaceutical localization

S Vallabhajosula, A Owunwanne - The pathophysiologic basis of nuclear …, 2006 - Springer
At the present time, the precise definition of disease is as complex as an exact definition of
life. It may be relatively more easy to define disease at a cellular and molecular level than at …

Involvement of transferrin in the uptake of 67Ga in inflammatory and normal tissues

Y Ohkubo, A Shibuya, H Kohno, A Kubodera - International Journal of …, 1989 - Elsevier
The results from gel chromatography and electrophoresis showed that 67 Ga is exclusively
bound with transferrin both in vitro and in vivo, but high concentrations of sodium citrate …

Transferrin is not involved in the entry of 67Ga into hepatocytes from regenerating liver of partially hepatectomized rats

S Abe, S Hasegawa, M Nirasawa… - Biological and …, 2001 - jstage.jst.go.jp
MATERIALS AND METHODS Animals Male Wistar rats weighing 180—250g (SLC,
Hamamatsu, Japan) were kept under conditions of a 12-h light–dark cycle, 231 C and 555 …

The effect of FeCl3 on the accumulation of gallium-67 into inflammatory and normal tissues

Y Ohkubo, S Araki, K Abe, S Takasu, H Kohno… - Annals of Nuclear …, 1988 - Springer
The effect of FeCl 3 on the uptake of 67 Ga by inflammatory and normal tissues was studied
to clarify the role of transferrin in 67 Ga uptake by inflammatory tissue. The administration of …