Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a …

WJ Powers, AA Rabinstein, T Ackerson, OM Adeoye… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

[HTML][HTML] Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and …

S Bernardo-Castro, JA Sousa, A Brás, C Cecília… - Frontiers in …, 2020 - frontiersin.org
The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …

Management of acute ischemic stroke

MS Phipps, CA Cronin - Bmj, 2020 - bmj.com
Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

[HTML][HTML] Hemorrhagic transformation in ischemic stroke and the role of inflammation

E Spronk, G Sykes, S Falcione, D Munsterman… - Frontiers in …, 2021 - frontiersin.org
Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

[HTML][HTML] Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis

Y Wang, H Niu, L Li, J Han, Z Liu, M Chu, X Sha… - Journal of …, 2023 - Springer
Ferroptosis plays a critical role in ischemic stroke, and anti-ferroptosis strategies were
regarded as potentially effective measures. Based on ferroptosis-related mechanisms, this …

[HTML][HTML] The role of immune cells in post-stroke angiogenesis and neuronal remodeling: the known and the unknown

Y Ma, S Yang, Q He, D Zhang, J Chang - Frontiers in immunology, 2021 - frontiersin.org
Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

Management of Intracerebral Hemorrhage: JACC Focus Seminar

M Schrag, H Kirshner - Journal of the American College of Cardiology, 2020 - jacc.org
Intracerebral hemorrhage (ICH) accounts for a disproportionate amount of stroke-related
morbidity and mortality. Although chronic hypertension and cerebral amyloid angiopathy are …

[HTML][HTML] Hemorrhagic transformation after ischemic stroke: mechanisms and management

JM Hong, DS Kim, M Kim - Frontiers in Neurology, 2021 - frontiersin.org
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Seizures after ischemic stroke: a matched multicenter study

C Ferreira‐Atuesta, N Döhler… - Annals of …, 2021 - Wiley Online Library
Objective The purpose of this study was to identify risk factors for acute symptomatic
seizures and post‐stroke epilepsy after acute ischemic stroke and evaluate the effects of …

Treatments in ischemic stroke: current and future

MG Mosconi, M Paciaroni - European neurology, 2022 - karger.com
Abstract Background and Aim: Despite progress made over the last 30 years, stroke is still a
leading cause of disability and mortality; likewise, its burden is expected to increase over the …